Transcutaneous electrical nerve stimulation and placebo analgesia: is the effect the same for young and older individuals? [PDF]
Clinical Interventions in Aging, 2018 Inès Daguet,1,2 Kayla Bergeron-Vézina,1,2 Marie-Philippe Harvey,1,2 Marylie Martel,1,2 Guillaume Léonard2,3 1Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, QC ...
Daguet I +4 more
doaj +3 more sources
Meta-analytic evidence for distinct neural correlates of conditioned versus verbally induced placebo analgesia [PDF]
Nature CommunicationsPlacebo analgesia demonstrates that belief and expectation can significantly alter pain, even without active treatment. Placebo analgesia can be induced through verbal suggestion, classical conditioning, or their combination, though the role of ...
Tamas Spisak +7 more
doaj +3 more sources
Are Individual Learning Experiences More Important Than Heritable Tendencies? A Pilot Twin Study on Placebo Analgesia [PDF]
Frontiers in Psychiatry, 2019 Objective: Predicting who will be a placebo responder is a prerequisite to maximize placebo effects in pain treatment and to minimize them in clinical trials. First evidence exists that genetics could affect placebo effects.
Katja Weimer +7 more
doaj +3 more sources
The Two Sides of Placebo Analgesia: Differential Functional Connectivity Reveals Mechanisms of Placebo Analgesic Response [PDF]
Journal of Pain ResearchNicholas J Bush,1,2 Adriana K Cushnie,2 Jeff Boissoneault,1,2 Sharmagh Aghabeigi,1 Casey Alexander,1 Roland Staud,3 Michael E Robinson1 1Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA; 2Department of ...
Bush NJ +6 more
doaj +4 more sources
Function and biochemistry of the dorsolateral prefrontal cortex during placebo analgesia: how the certainty of prior experiences shapes endogenous pain relief [PDF]
Cereb Cortex, 2023 Prior experiences, conditioning cues, and expectations of improvement are essential for placebo analgesia expression. The dorsolateral prefrontal cortex is considered a key region for converting these factors into placebo responses.
L. Crawford +5 more
semanticscholar +2 more sources
Placebo Analgesia Reduces Costly Prosocial Helping to Lower Another Person’s Pain [PDF]
Psychol Sci, 2022 Painkiller administration lowers pain empathy, but whether this also reduces prosocial behavior is unknown. In this preregistered study, we investigated whether inducing analgesia through a placebo painkiller reduced effortful helping.
Helena Hartmann +3 more
semanticscholar +2 more sources
Manipulating placebo analgesia and nocebo hyperalgesia by changing brain excitability [PDF]
Proc Natl Acad Sci U S A, 2021 Significance Although previous studies have extensively studied the neurobiological mechanisms of placebo and nocebo effects, ways to manipulate these effects to yield further benefits remain relatively unknown.
Y. Tu +8 more
semanticscholar +2 more sources
The Effect of the Model’s Social Status on Placebo Analgesia Induced by Social Observational Learning [PDF]
Pain Med, 2021 Background Placebo analgesia can be induced by social observational learning. The aim of this study was to determine whether this effect can be influenced by the social status of a model. Methods Healthy volunteers were randomly assigned to three groups:
H. Bieniek, P. Bąbel
semanticscholar +2 more sources
Opioidergic activation of the descending pain inhibitory system underlies placebo analgesia [PDF]
Sci AdvPlacebo analgesia is caused by inactive treatment, implicating endogenous brain function involvement. However, the neurobiological basis remains unclear.
Hiroyuki Neyama +17 more
semanticscholar +2 more sources
Selective REM Sleep Deprivation Improves Expectation-Related Placebo Analgesia.
PLoS ONE, 2015 The placebo effect is a neurobiological and psychophysiological process known to influence perceived pain relief. Optimization of placebo analgesia may contribute to the clinical efficacy and effectiveness of medication for acute and chronic pain ...
Florian Chouchou +3 more
doaj +2 more sources