"On Suggestion" by John Bostock, 1923: A comparison with twenty-first century understandings of the placebo effect. [PDF]
Australas Psychiatry, 2023 Clayton A.
europepmc +1 more source
Arthritis &Rheumatology, Accepted Article.Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to three years; all patients received mycophenolate mofetil and low‐dose ...
Brad H. Rovin +9 more
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The Placebo Effect in Psychosis: Why It Matters and How to Measure It. [PDF]
Biol Psychiatry Glob Open Sci, 2023 Hird EJ +4 more
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Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and TYK2 Inhibitors via IL10 Antagonism
Arthritis &Rheumatology, Accepted Article.Background JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but TYK2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn's Disease, which highlights the complex role for JAK‐STAT signaling in different inflammatory processes. In this study, we investigated
Sami Giryes +14 more
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Presenting a sham treatment as personalised increases the placebo effect in a randomised controlled trial. [PDF]
Elife, 2023 Sandra DA, Olson JA, Langer EJ, Roy M.
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Arthritis &Rheumatology, Accepted Article.Objective The SEMAPHORE trial evaluated the efficacy and safety of tocilizumab (TCZ) in glucocorticoid (GC)‐dependent polymyalgia rheumatica (PMR). TCZ reduced GC use and disease activity at 24 weeks. This study aimed to assess relapse rates after stopping TCZ in patients achieving remission at week 24.
Baptiste Chevet +24 more
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Harnessing the placebo effect to enhance emotion regulation effectiveness and choice. [PDF]
Sci Rep, 2023 Shafir R, Israel M, Colloca L.
europepmc +1 more source
DFN-02, Sumatriptan 10 mg Nasal Spray with Permeation Enhancer, for the Acute Treatment of Migraine: A Randomized, Double-Blind, Placebo-Controlled Study Assessing Functional Disability and Subject Satisfaction with Treatment. [PDF]
, 2019 BackgroundThe commercial formulation of sumatriptan nasal spray is an effective option for migraine patients requiring or preferring a non-oral route of drug administration, but its utility is limited by poor absorption and tolerability issues. DFN-02, a
Brand-Schieber, Elimor +3 more
core
Cold water immersion after a soccer match: Does the placebo effect occur? [PDF]
Front Physiol, 2023 Nasser N +3 more
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Mucosal‐associated invariant T cells in rheumatic diseases.
Arthritis &Rheumatology, Accepted Article.Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor (TCR) and restriction by the MHC class I‐related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines. Upon activation, MAIT cells rapidly produce pro‐inflammatory cytokines,
Manon Lesturgie‐Talarek +7 more
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