Results 191 to 200 of about 728,357 (259)
Clinical Pharmacology &Therapeutics, EarlyView.Lysergic acid diethylamide (LSD) is currently being investigated as a potential treatment for psychiatric and neurological disorders. Different LSD formulations (base or tartrate, oral or intravenous) are being used. Unclear is whether LSD base and tartrate pharmacokinetics are equivalent.
Denis Arikci +7 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Pazopanib is an oral tyrosine kinase inhibitor used in patients with either metastatic renal cell carcinoma or soft tissue sarcoma. Pazopanib has a high interindividual variability in pharmacokinetics and pharmacodynamics and a well‐established exposure–response relationship. Therefore, therapeutic drug monitoring is recommended to improve the efficacy–
Amy Rieborn +6 more
wiley +1 more source
Examining the Financial Impact of Biodiversity‐Related Reputational Disasters
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT This research investigates the reaction of financial markets to biodiversity‐related corporate events, utilising an EGARCH model to assess the implications on stock returns and volatility. Results reveal that markets significantly respond to these events, demonstrating heightened sensitivity and volatility that underscore the financial ...
Erdinc Akyildirim, Shaen Corbet
wiley +1 more source
Cytometry Part B: Clinical Cytometry, EarlyView.ABSTRACT Anticipating the evolution of septic patients with community‐acquired pneumonia (CAP) is challenging for front‐line physicians in the Emergency Department (ED). Prognosis depends mainly on early identification, antibiotics, organ support, but also immune status.
Thomas Lafon +4 more
wiley +1 more source
Placebo Effect in the Treatment of Depression and Anxiety. [PDF]
Front Psychiatry, 2019 Kirsch I.
europepmc +1 more source
Drug Testing and Analysis, EarlyView.Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis +2 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.The study provides information about the impact of physiological gastric conditions on the unbeneficial occurrence of nitrosamine drug substance–related impurities (NDSRIs). Both main factors for nitrosation in the form of acidic conditions and the presence of nitrite were adequately chosen for triggering the conversion of drug compounds into NDSRIs ...
Matthias Vogel +5 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective To develop and test the effectiveness of the eBEfree program, a 12‐session app‐based version of a previously tested psychological intervention (BEfree) that combines psycho‐education, self‐compassion, mindfulness, and Acceptance and Commitment Therapy to reduce binge‐eating symptoms.
Hugo Senra +11 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Cognitive‐behavioral therapy (CBT) is the most well‐established treatment for binge‐eating disorder (BED), but the mechanisms of change remain poorly understood. This study investigated in CBT for BED the effects of overvaluation of shape and weight and dietary restraint on subsequent objective binge‐eating episodes (OBEs). Method In
Ricarda Schmidt +8 more
wiley +1 more source
Role of selenium in the pathophysiology of cardiorenal anaemia syndrome
ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai +2 more
wiley +1 more source