Results 221 to 230 of about 14,611,928 (419)

Lecanemab‐Associated Amyloid‐β Protofibril in Cerebrospinal Fluid Correlates with Biomarkers of Neurodegeneration in Alzheimer's Disease

Annals of Neurology, EarlyView.
Objective The Clarity AD phase III trial showed that lecanemab reduced amyloid markers in early Alzheimer's disease (AD) and resulted in less decline on measures of cognition and function than placebo. Herein, we aimed to characterize amyloid‐β (Aβ) protofibril (PF) captured by lecanemab in human cerebrospinal fluid (CSF) from living participants with ...
Moeko Noguchi‐Shinohara, Kazuyoshi Shuta, Hidetomo Murakami, Yukiko Mori, Junji Komatsu, Chizuru Kobayashi, Steven Hersch, Kanta Horie, Kenjiro Ono   +8 more
wiley   +1 more source

Placebo, nocebo: Believing in the field of medicine

Frontiers in Pain Research, 2022
Karin Meissner, Karin Meissner
doaj   +1 more source

n-3 PUFAs for depression: treatment effect or absence-of-placebo effect? [PDF]

Transl Psychiatry, 2022
Memarpouri A, van der Does W, Molendijk ML.   +2 more
europepmc   +1 more source

The effect of docosahexaenoic acid on aggression in young adults. A placebo-controlled double-blind study. [PDF]

, 1996
Tomohito Hamazaki, Shigeki Sawazaki, Miho Itomura, Etsuko Asaoka, Yoko Nagao, Nobuhiro Nishimura, Kazunaga Yazawa, Toyomi Kuwamori, Makoto Kobayashi   +8 more
openalex   +1 more source

Brain Metabolic Features of FUS‐ALS: A 2‐[18F]FDG‐PET Study

Annals of Neurology, EarlyView.
Objective We aimed at evaluating the brain metabolic features of fused in sarcoma amyotrophic lateral sclerosis (FUS‐ALS) compared with sporadic ALS (sALS), using 2‐[fluorine‐18] fluoro‐2‐deoxy‐D‐glucose positron emission tomography (2‐[18F]FDG‐PET). Methods We employed the 2‐sample t‐test model of SPM12, implemented in MATLAB, to compare 12 FUS‐ALS ...
Antonio Canosa, Umberto Manera, Rosario Vasta, Grazia Zocco, Francesca Di Pede, Sara Cabras, Filippo De Mattei, Francesca Palumbo, Barbara Iazzolino, Emilio Minerva, Luca Sbaiz, Maura Brunetti, Salvatore Gallone, Maurizio Grassano, Enrico Matteoni, Giulia Polverari, Giuseppe Fuda, Federico Casale, Paolina Salamone, Giovanni De Marco, Giulia Marchese, Cristina Moglia, Andrea Calvo, Marco Pagani, Adriano Chiò   +24 more
wiley   +1 more source

Interleukin 6/gp130 axis promotes neural invasion in pancreatic cancer

Cancer Medicine, Volume 11, Issue 24, Page 5001-5012, December 2022., 2022
Nerve invasion (N‐inv) is an important prognostic factor in pancreatic ductal adenocarcinoma (PDAC). To elucidate circulating stimulators for nerve invasion, the authors evaluated the stimulant activity and the inhibitory effects of IL‐6/gp130 axis. Biological activity of IL‐6/gp130 axis promoted nerve invasion in murine model and was upregulated in ...
Hidetaka Suzuki, Shuichi Mitsunaga, Masafumi Ikeda, Takao Aoyama, Kazumi Yoshizawa, Masayuki Yamaguchi, Masami Suzuki, Minoru Narita, Toshikatsu Kawasaki, Atsushi Ochiai   +9 more
wiley   +1 more source

Editorial: Placebo Effect in Pain and Pain Treatment. [PDF]

Front Pain Res (Lausanne), 2022
Bernstein MH, Blease C, Vase L.
europepmc   +1 more source

The Effect of Maternal Supplementation with Linoleic and .GAMMA.-Linolenic Acids on the Fat Composition and Content of Human Milk: A Placebo-Controlled Trial.

, 1991
Andrew J. Cant, Janet Shay, David F. Horrobin   +2 more
openalex   +2 more sources

Effect of homoeopathy on pain and other events after acute trauma: placebo controlled trial with bilateral oral surgery [PDF]

, 1995
P Løkken, P Straumsheim, D Tveiten, Per Skjelbred, C F Borchgrevink   +4 more
openalex   +1 more source

Plasma Glucosylceramide Levels Are Regulated by ATP10D and Are Not Involved in Parkinson's Disease Pathogenesis

Annals of Neurology, EarlyView.
GBA1 variants and decreased glucocerebrosidase activity are implicated in Parkinson's disease (PD). We investigated the hypothesis that increased levels of glucosylceramide (GlcCer), a main substrate of glucocerebrosidase, are involved in PD pathogenesis.
Emma N. Somerville, Alva James, Christian Beetz, Robert Schwieger, Gal Barrel, Krishna K. Kandaswamy, Marius I. Iurascu, Peter Bauer, Michael Ta, Hirotaka Iwaki, Konstantin Senkevich, Eric Yu, Roy N. Alcalay, Ziv Gan‐Or   +13 more
wiley   +1 more source