Results 101 to 110 of about 5,256,450 (257)

Historical Aspects of Placebo Analgesia

open access: yes, 2013
The placebo effect has been a topic of interest in medicine for many hundreds of years. A historical evaluation of the topic demonstrates how the origin of the word, and its initial use in society and in medicine, has shaped its meaning over many years ...
Damien Finniss, Finniss, Damien
core   +1 more source

Placebo and nocebo effects in sport [PDF]

open access: yes, 2023
Placebo and nocebo effects can significantly influence sport performance. In the past two decades, research has identified various neurobiological mechanisms of its response and how an athlete’s expectation and previous experiences, can alter the ...
Hurst, P.
core  

AA Placebo Response Rate Supplement

open access: yes, 2021
AA Placebo Response Rate ...
han, J (via Mendeley Data)
core   +1 more source

PTBP1‐Mediated Alternative Splicing of DNAJB6 Promotes Everolimus Resistance in Clear Cell Renal Cell Carcinoma via EIF4B/PKIB/AKT/mTOR Positive Feedback Loop

open access: yesAdvanced Science, EarlyView.
PTBP1‐mediated alternative splicing drives a pathogenic switch to the DNAJB6b isoform in everolimus‐resistant clear cell renal cell carcinoma. This splicing event programs a positive feedback loop including EIF4B/PKIB/AKT/mTOR, promoting aggressive therapy resistance.
Xiu‐wu Pan   +18 more
wiley   +1 more source

Is placebo analgesia for heat pain a sensory effect? An exploratory study on minimizing the influence of response bias

open access: yesNeurobiology of Pain, 2019
We explored the ongoing question of whether placebo analgesia alters afferent nociceptive processing in a novel paradigm designed to minimize the role of response bias in placebo measurement.
Laura K. Case   +6 more
doaj   +1 more source

Hydrocortisone therapy for patients with septic shock [PDF]

open access: yes, 2008
Background Hydrocortisone is widely used in patients with septic shock even though a survival benefit has been reported only in patients who remained hypotensive after fluid and vasopressor resuscitation and whose plasma cortisol levels did not rise ...
Sprung, Charles L   +19 more
core   +1 more source

Co‐activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee   +3 more
wiley   +1 more source

Do cognitive bias and heuristics influence improvement in knee pain in patients with knee osteoarthritis treated with open label placebo? The CHIPS study - An exploratory study using questionnaire and group concept mapping

open access: yesOsteoarthritis and Cartilage Open
Objective: This study explored if the patient-experience and the affect heuristic influenced improvements in painful symptoms, in response to open label placebo injections in patients with knee OA.
Tommy Kok Annfeldt   +5 more
doaj   +1 more source

The Placebo Hypoalgesic Response Is Reduced in Healthy Older Adults Showing a Decline in Executive Functioning [PDF]

open access: yes
Katharina M Rischer,1 Angelika M Dierolf,1 Fernand Anton,1 Pedro Montoya,2 Ana M González-Roldán,2 Marian van der Meulen1 1Department of Behavioural and Cognitive Sciences, Institute for Health and Behaviour, University of Luxembourg, Esch-sur-Alzette ...
Montoya P   +5 more
core  

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

open access: yesAdvanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang   +15 more
wiley   +1 more source

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