Results 111 to 120 of about 5,256,450 (257)

Rethinking placebo in psychiatry: The range of placebo effects

, 2013
This article, the first of two on placebo effects, provides a broad overview of placebo in the field of medicine. A brief conceptual history is followed by some basic facts about placebos. Problems of definition are identified.
St John-Smith, Paul, Rampes, Hagen, McQueen, Daniel, Cohen, Sarah   +3 more
core   +1 more source

Single‐Cell Transcriptomic Profiling Identifies B Cell‐Intrinsic Dysregulation of Sphingolipid Biosynthesis and Could Be Improved by Inhibiting UGCG in Primary Immune Thrombocytopenia

Advanced Science, EarlyView.
This study generates the single‐cell atlas of pathogenic B‐cell subset Bc‐5 in ITP. It identifies RUNX3 as a key survival regulator and uncovers sphingolipid‐driven metabolic reprogramming, validating UGCG inhibition as a therapeutic candidate and building a valuable resource for ITP mechanistic and therapeutic exploration.
Dongmei Luo, Yanxia Zhan, Lili Ji, Pengcheng Xu, Pu Chen, Hao Pang, Yunan Ling, Fanli Hua, Xibing Zhuang, Hao Chen, Yunfeng Cheng   +10 more
wiley   +1 more source

Re-evaluating the placebo response in recent canine dietary epilepsy trials

BMC Veterinary Research
The placebo response is a common phenomenon. Limited evidence is available about its magnitude in canine epilepsy trials, even though it can significantly influence the efficacy evaluation of new treatments.
Teresa Schmidt, Nina Meyerhoff, Sebastian Meller, Friederike Twele, Marios Charalambous, Benjamin A. Berk, Tsz H. Law, Rowena M. A. Packer, Brian Zanghi, Yuanlong Pan, Andrea Fischer, Holger A. Volk   +11 more
doaj   +1 more source

The concept of placebo/nocebo response and effect

EULAR Rheumatology Open
: The placebo response is different from the placebo effect. Whereas the placebo response is the global response to a placebo, including spontaneous remission, regression to the mean, patients’ and experimenters’ biases, possible effects of ...
Fabrizio Benedetti
doaj   +1 more source

Rational Expectations and Market Timing: An Event Study of the China–United States Phase One Trade Deal

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Rational actors constantly incorporate information into their decision‐making behavior. Since there is often a time lag between the announcement of a policy and its implementation, an important question arises: when do rational actors incorporate new information into their market behavior, at the announcement or at the implementation of a ...
Tim Ölkers, Oliver Mußhoff
wiley   +1 more source

Placebo Analgesia in Rodents

, 2014
The placebo effect is a fascinating yet puzzling phenomenon which has challenged investigators over the past 50 years. Some researchers have initiated investigations of the effects of placebos in animals, and have shown that associative learning is a ...
Jian-You Guo, Fei Luo, Jin-Yan Wang
core   +1 more source

The placebo response in social phobia

, 2001
The placebo response forms a growing problem in randomized, placebo-controlled clinical trials in psychiatry. Research into the placebo response is on the increase, but remains very limited in relation to social phobia.
van Balkom, Anton J.L.M., Spinhoven, Philip, van Dyck, Richard, Oosterbaan, Désirée B.   +3 more
core   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Editorial: Placebo Effect in Pain and Pain Treatment

Frontiers in Pain Research, 2022
Michael H. Bernstein, Charlotte Blease, Lene Vase   +2 more
doaj   +1 more source

Growth of Omnichannel Grocery Retailing and Food Prices

Agribusiness, EarlyView.
ABSTRACT This paper examines the effects of the growth of omnichannel grocery retailing on food prices. We first develop a conceptual model of consumer choice and retailer pricing that allows us to evaluate changes in equilibrium prices, quantities, and profits with online channel growth and alternative pricing strategies.
Xiangwen Kong, Metin Çakır, Qingxiao Li   +2 more
wiley   +1 more source