Results 21 to 30 of about 361,365 (49)
Health, 2018 Research suggests that a ‘placebo’ can improve conditions common in primary care including pain, depression and irritable bowel syndrome. However, disagreement persists over the definition and clinical relevance of placebo treatments. We conducted a meta-
Doug I Hardman +5 more
semanticscholar +1 more source
Problematic placebos in physical therapy trials.
Journal of Evaluation In Clinical Practice, 2016 The function of a placebo control in a randomised trial is to permit blinding and reduce risk of bias. Adopting Grűnbaum’s definitional scheme of a placebo, all treatments must be viewed as packages consisting of characteristic and incidental features ...
M. Maddocks +3 more
semanticscholar +1 more source
Different Placebos, Different Mechanisms, Different Outcomes: Lessons for Clinical Trials
PLoS ONE, 2015 Clinical trials use placebos with the assumption that they are inert, thus all placebos are considered to be equal. Here we show that this assumption is wrong and that different placebo procedures are associated to different therapeutic rituals which, in
F. Benedetti, Sara Dogue
semanticscholar +1 more source
Placebos without Deception: A Randomized Controlled Trial in Irritable Bowel Syndrome
PLoS ONE, 2010 Background Placebo treatment can significantly influence subjective symptoms. However, it is widely believed that response to placebo requires concealment or deception. We tested whether open-label placebo (non-deceptive and non-concealed administration)
T. Kaptchuk +11 more
semanticscholar +1 more source
Steps to Strengthen Ethics in Organizations: Research Findings, Ethics Placebos, and What Works
Journal of Trauma & Dissociation, 2015 Research shows that many organizations overlook needs and opportunities to strengthen ethics. Barriers can make it hard to see the need for stronger ethics and even harder to take effective action. These barriers include the organization’s misleading use
K. Pope
semanticscholar +1 more source
Paternalism, Placebos, and Informed Consent in Psychotherapy
, 2016 From a legal as well as ethical point of view, healthcare professionals are nowadays obliged to obtain informed consent (IC) of patients. Consequently, paternalism is eschewed in most ethical codes of practice and IC.
C. Blease, M. Trachsel, M. Holtforth
semanticscholar +1 more source
BMJ Open, 2015 Introduction Placebos have long provided a robust control for evaluating active pharmacological preparations, but frequently demonstrate a variable therapeutic effect when delivered in double-blinded placebo-controlled trials.
G. Petkovic +5 more
semanticscholar +1 more source
Are Treatments More Effective than Placebos? A Systematic Review and Meta-Analysis
PLoS ONE, 2013 Background Placebos are widely used in clinical practice in spite of ethical restrictions. Whether such use is justified depends in part on the relative benefit of placebos compared to ‘active’ treatments.
J. Howick +8 more
semanticscholar +1 more source
Lying to win-placebos and sport science.
International Journal of Sports Physiology and Performance, 2013 introduce an intrigu-ing Thomas Jefferson quote from 1807 addressing “pious fraud”: “One of the most successful physicians I have ever known has assured me that he used more bread pills, drops of colored water, and powders of hickory ashes, than of all ...
S. Halson, David T. Martin
semanticscholar +1 more source
PLoS ONE, 2012 Background Placebo groups are used in randomised clinical trials (RCTs) to control for placebo effects, which can be large. Participants in trials can misunderstand written information particularly regarding technical aspects of trial design such as ...
F. Bishop +3 more
semanticscholar +1 more source