Results 231 to 240 of about 24,941 (289)
ADAM17 and its proteolytic targets in disease pathogenesis
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
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Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Therapy of feto-placental insufficiency with xanthinol-nicothinate,glucose and insulin
CARLOMAGNO, Giorgio +4 more
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Dialysis and Pregnancy: Optimizing Therapy for Best Maternal and Fetal Outcomes
ABSTRACT Pregnancy in women with end‐stage kidney disease (ESKD) requiring dialysis remains high risk, with significant maternal and fetal complications. While fertility rates are markedly reduced in this population, advances in dialysis care and obstetric management have led to increasing reports of successful pregnancies.
Shreepriya Mangalgi, Silvi Shah
wiley +1 more source
info:eu-repo/semantics ...
Wilkin, Paul
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The role of melatonin in pregnancies complicated by placental insufficiency: A systematic review [PDF]
Placental insufficiency affects about 10% of pregnancies and can lead to pre-eclampsia, fetal growth restriction, and preterm birth. Despite significant advances in early prediction and prevention of preterm pre-eclampsia with aspirin, the effects of ...
Ilaria Fantasia +2 more
exaly +2 more sources
Nanomedicines: An approach to treat placental insufficiency and the current challenges [PDF]
INTRODUCTION: Preeclampsia and fetal growth restriction are common pregnancy complications that significantly impact perinatal health and offspring development later in life.
A T Lely
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Placental insufficiency is a major problem worldwide for both mothers and babies. However, we have demonstrated in a review of the biomedical literature, that both the terminology used to describe, and techniques used to measure suboptimal placental ...
Stephen Kennedy, Manu Vatish
exaly +2 more sources
Unfractionated heparin for second trimester placental insufficiency: a pilot randomized trial
Objective: To conduct a pilot randomized controlled trial of unfractionated heparin (UFH) in women considered at high risk of placental insufficiency in the second trimester. Methods: Women with either false-positive first trimester (pregnancy-associated
J C P Kingdom, M Walker, Sarah Keating
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Placental insufficiency and postmaturity
European Journal of Obstetrics & Gynecology and Reproductive Biology, 1975Full placental development and functioning are achieved around the 5th month of gestation. Thereafter, until birth, signs of gradual placental aging are observed which are partly compensated by an increase in trophoblastic surface area to maintain adequate fetal oxygen and nutrient supply (Krantz and Kubli, 1967; Hellegers, 1969).
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