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ABSTRACT Background Moderate‐to‐severe thrombocytopenia (platelet count < 100 × 109/L) occurs in fewer than 1% of pregnancies, posing management challenges, particularly surrounding eligibility for neuraxial anesthesia. Although recent anesthesia guidelines recommend a platelet threshold ≥ 70 × 109/L, outcomes data applying these recommendations in ...
Mackenzie E. Lemieux, Ming Y. Lim
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Coagulation and Fibrinolysis in Normal Pregnancy and Complicated Pregnancy
ABSTRACT Introduction Pregnancy induces significant physiological changes in the hemostatic system, leading to a hypercoagulable state to prevent postpartum hemorrhage. These adaptations involve alterations in coagulation and fibrinolysis, which can be further modified in complicated pregnancies such as gestational diabetes mellitus (GDM) and ...
Yang Su +6 more
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Acute placental insufficiency two weeks after an asymptomatic COVID-19 maternal infection: the deleterious effects of the SARS-CoV-2 placentitis. [PDF]
Delle Chiaie L +3 more
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Wilkin, Paul
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Leptin: A Potential Marker of Placental Insufficiency
Gynecologic and Obstetric Investigation, 2003To investigate placental leptin production in placental insufficiency, placental leptin production was measured in women with severe preeclampsia (group 1) and in normotensive pregnancies associated with intrauterine growth restriction (group 2), compared to controls (group 3).
Jacques Lepercq +2 more
exaly +3 more sources
Placental insufficiency is a major problem worldwide for both mothers and babies. However, we have demonstrated in a review of the biomedical literature, that both the terminology used to describe, and techniques used to measure suboptimal placental ...
Manu Vatish +2 more
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The Role of Melatonin in Pregnancies Complicated by Placental Insufficiency: A Systematic Review [PDF]
Placental insufficiency affects about 10% of pregnancies and can lead to pre-eclampsia, fetal growth restriction, and preterm birth. Despite significant advances in early prediction and prevention of preterm pre-eclampsia with aspirin, the effects of ...
Tamara Stampalija +2 more
exaly +2 more sources
Placental insufficiency and postmaturity
European Journal of Obstetrics & Gynecology and Reproductive Biology, 1975Full placental development and functioning are achieved around the 5th month of gestation. Thereafter, until birth, signs of gradual placental aging are observed which are partly compensated by an increase in trophoblastic surface area to maintain adequate fetal oxygen and nutrient supply (Krantz and Kubli, 1967; Hellegers, 1969).
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Elevated circulating and placental SPINT2 is associated with placental insufficiency
Placenta, 2021No description ...
Murphy, Ciara +13 more
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