Embryonic Heart and Skin Defects in Mice Lacking Plakoglobin
Developmental Biology, 1996 Plakoglobin is the only component common to both the desmosomal plaque and the cadherin-catenin cell adhesion complex in the adherens junction. It is highly homologous to vertebrate beta-catenin and to Drosophila armadillo protein and may-like these proteins-be also involved in signaling pathways.
Bierkamp, C. +4 more
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Exercise and the heart: unmasking Mr Hyde [PDF]
, 2015 As physicians, we often face patients with cardiovascular risk factors or different kinds of heart disease. We prescribe statins, ACE inhibitors or β-blockers, but also (should) encourage our patients to engage in regular physical activity to reduce ...
Guasch i Casany, Eduard +1 more
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Cytoplasmically Anchored Plakoglobin Induces a WNT-like Phenotype inXenopus
Developmental Biology, 1997 Plakoglobin is one of two vertebrate proteins closely related to the Drosophila segment polarity gene product armadillo. Overexpression of plakoglobin induces neural axis duplication in Xenopus and the exogenous plakoglobin is localized to nuclei (Karnovsky, A., and Klymkowsky, M. W., Proc. Natl. Acad. Sci.
Merriam, John M. +2 more
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Regulation of cardiovascular connexins by mechanical forces and junctions [PDF]
, 2017 Connexins form a family of transmembrane proteins that consists of 20 members in humans and 21 members in mice. Six connexins assemble into a connexon that can function as a hemichannel or connexon that can dock to a connexon expressed by a neighbouring ...
Delmar, Mario +3 more
core
The progestin receptor interactome in the female mouse hypothalamus: Interactions with synaptic proteins are isoform specific and ligand dependent [PDF]
, 2017 Progestins bind to the progestin receptor (PR) isoforms, PR-A and PR-B, in brain to influence development, female reproduction, anxiety, and stress. Hormone-activated PRs associate with multiple proteins to form functional complexes. In the present study,
Acharya, Kalpana D +12 more
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Premature Termination Codon in 5′ Region of Desmoplakin and Plakoglobin Genes May Escape Nonsense-Mediated Decay through the Reinitiation of Translation [PDF]
, 2022 Marta Vallverdú-Prats +2 more
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Desmoglein 3: a help or a hindrance in cancer progression? [PDF]
, 2015 Desmoglein 3 is one of seven desmosomal cadherins that mediate cell-cell adhesion in desmosomes. Desmosomes are the intercellular junctional complexes that anchor the intermediate filaments of adjacent cells and confer strong cell adhesion thus are ...
Ambrosch +14 more
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Genetic bases of arrhythmogenic right ventricular cardiomyopathy
Heart International, 2010 Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heart muscle disease in which the pathological substrate is a fibro-fatty replacement of the right ventricular myocardium.
Alessandra Rampazzo
doaj +1 more source
Presenilin-1 Interacts with Plakoglobin and Enhances Plakoglobin-Tcf-4 Association [PDF]
Journal of Biological Chemistry, 2006 Imma Raurell +4 more
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Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin. [PDF]
, 1995 Alla Karnovsky, Michael W. Klymkowsky
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