A New Perspective on Intercalated Disc Organization: Implications for Heart Disease
Adherens junctions and desmosomes are intercellular adhesive junctions and essential for the morphogenesis, differentiation, and maintenance of tissues that are subjected to high mechanical stress, including heart and skin.
Jifen Li, Glenn L. Radice
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A Central Role for the Armadillo Protein Plakoglobin in the Autoimmune Disease Pemphigus Vulgaris [PDF]
Reto Caldelari +6 more
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Pathogenesis in Pemphigus Vulgaris: A Central Role for the Armadillo Protein Plakoglobin. [PDF]
Eliane J. Müller +6 more
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Mechanisms of Plakoglobin-dependent Adhesion [PDF]
Taofei Yin +6 more
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Patterns in Space: Coordinating Adhesion and Actomyosin Contractility at E-cadherin Junctions
Cadherin adhesion receptors are fundamental determinants of tissue organization in health and disease. Increasingly, we have come to appreciate that classical cadherins exert their biological actions through active cooperation with the contractile actin ...
Wu, Selwin K., Yap, Alpha S.
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The toxicity of environmental and dietary ligands of the aryl hydrocarbon receptor (AhR) in mature liver parenchymal cells is well appreciated, while considerably less attention has been paid to their impact on cell populations exhibiting phenotypic ...
Jan Vondráček, Miroslav Machala
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Presenilin-1 interacts with plakoglobin and enhances plakoglobin-Tcf-4 association. IMPLICATIONS FOR THE REGULATION OF β-CATENIN/Tcf-4-DEPENDENT TRANSCRIPTION. [PDF]
Imma Raurell +4 more
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Distinct ligand binding sites in integrin alpha3beta1 regulate matrix adhesion and cell-cell contact. [PDF]
The integrin alpha3beta1 mediates cellular adhesion to the matrix ligand laminin-5. A second integrin ligand, the urokinase receptor (uPAR), associates with alpha3beta1 via a surface loop within the alpha3 beta-propeller (residues 242-246) but outside ...
Chapman, Harold A +6 more
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Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis [PDF]
To contribute to an understanding of the roles and mechanisms of action of Wnts in early vertebrate development, we have characterized the normal expression of Xenopus laevis Wnt-5A, and investigated the consequences of misexpression of this putative ...
Campbell, Robert M. +5 more
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