Single-Cell RNA Sequencing of PBMCs Identified Junction Plakoglobin (JUP) as Stratification Biomarker for Endometriosis. [PDF]
Int J Mol SciAndrieu T +8 more
europepmc +2 more sources
Gastroenterology, 2023 BACKGROUND AND AIMS Colon cancer patients with liver metastases may be cured by surgery, but the presence of additional lung metastases often precludes curative treatment. Little is known about the processes driving lung metastasis.
Emre Küçükköse +20 more
semanticscholar +1 more source
Cardiovascular Electrophysiology, 2023 Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare inherited disorder usually affecting the right ventricle (RV), characterized by fibro‐fatty tissue replacement of the healthy ventricular myocardium.
Daniel Zinkovsky, Michael R Sood
semanticscholar +1 more source
Whole-Exome Sequencing Identified a De Novo Mutation of Junction Plakoglobin (p.R577C) in a Chinese Patient with Arrhythmogenic Right Ventricular Cardiomyopathy [PDF]
BioMed Research International, 2019 Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare and potentially life-threatening disorder of the heart. The clinical spectrum of ARVC includes myocyte loss and fibro-fatty tissue replacement.
Lv Liu, Chan Chen, Yali Li, Rong Yu
openalex +2 more sources
Beta-Catenin and Plakoglobin Expression during Zebrafish Tooth Development and Replacement. [PDF]
PLoS ONE, 2016 We analyzed the protein distribution of two cadherin-associated molecules, plakoglobin and β-catenin, during the different stages of tooth development and tooth replacement in zebrafish.
Barbara Verstraeten +2 more
doaj +1 more source
Plakoglobin as a Regulator of Desmocollin Gene Expression [PDF]
Journal of Investigative Dermatology, 2013 Desmosomes are cell adhesion junctions required for the normal development and maintenance of mammalian tissues and organs such as the skin, skin appendages, and the heart. The goal of this study was to investigate how desmocollins (DSCs), transmembrane components of desmosomes, are regulated at the transcriptional level.
Etienne Tokonzaba +7 more
openaire +3 more sources
Cheek-Pro-Heart: What Can the Buccal Mucosa Do for Arrhythmogenic Cardiomyopathy?
Biomedicines, 2023 Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease associated with ventricular arrhythmias and a high risk of sudden cardiac death (SCD). Although the disease was described over 40 years ago, its diagnosis is still difficult.
Carlos Bueno-Beti, Angeliki Asimaki
doaj +1 more source
Describing and Mapping the Research Trend of Scientific Publications on Arrhythmogenic Right Ventricular Cardiomyopathy Across Four Decades: A Bibliometric Analysis. [PDF]
Clin CardiolNote: The graphical abstract of the study. ABSTRACT Objectives To perform a bibliometric analysis of publications of arrhythmogenic right ventricular cardiomyopathy (ARVC) from 1981 to 2023 to summarize the current publications and explore frontiers on this topic.
Mo L, Sia CH, Lin W, Zheng X, Peng K.
europepmc +2 more sources
Micropapillary structure: A natural tumor collective invasion model with enhanced stem-like properties. [PDF]
Cancer SciBy analyzing the cancer stem‐like phenotype, multiomics features, and molecular mechanisms of cell cluster formation and collective invasion of micropapillary carcinoma, and integrating the vascular and immune microenvironment of micropapillary carcinoma, it is suggested that micropapillary carcinoma has the potential to become a solid tumor model for ...
Li S +9 more
europepmc +2 more sources
The Amino-terminal Domain of Desmoplakin Binds to Plakoglobin and Clusters Desmosomal Cadherin–Plakoglobin Complexes [PDF]
The Journal of Cell Biology, 1997 The desmosome is a highly organized plasma membrane domain that couples intermediate filaments to the plasma membrane at regions of cell–cell adhesion. Desmosomes contain two classes of cadherins, desmogleins, and desmocollins, that bind to the cytoplasmic protein plakoglobin.
Mitchell F. Denning +7 more
openaire +3 more sources