Results 71 to 80 of about 9,804 (231)

Ovarian Blood Sampling Identifies Junction Plakoglobin as a Novel Biomarker of Early Ovarian Cancer

Frontiers in Oncology, 2020
Ovarian cancer is the most lethal gynecologic malignancy. Early detection would improve survival, but an effective diagnostic test does not exist. Novel biomarkers for early ovarian cancer diagnosis are therefore warranted.
Florian Weiland, Florian Weiland, Florian Weiland, Noor A. Lokman, Manuela Klingler-Hoffmann, Thomas Jobling, Andrew N. Stephens, Andrew N. Stephens, Karin Sundfeldt, Peter Hoffmann, Martin K. Oehler, Martin K. Oehler, Martin K. Oehler   +12 more
doaj   +1 more source

Studies relating to protein expression in the uterus of the cow [PDF]

, 2007
End of project reportEmbryo loss is a major cause of reproductive wastage in the cow. The majority of embryo loss occurs in the first 16 days after fertilisation when the embryo is critically dependent on the maternal uterine environment for survival ...
Costello, L.M., Diskin, Michael G., Hynes, A.C., Morris, Dermot G., Sreenan, J.M.   +4 more
core  

Datasets for generic relation extraction [PDF]

, 2012
A vast amount of usable electronic data is in the form of unstructured text. The relation extraction task aims to identify useful information in text (e.g.
Aone, B. HACHEY, Bizer, Blei, C. GROVER, Chinchor, Cohen, Conrad, Curran, Doddington, Filatova, Grover, Hachey, Hasegawa, Heimonen, Lin, Marcus, McDonald, Minnen, Mitchell, Pustejovsky, R. TOBIN, Smith, Walker   +23 more
core   +1 more source

Unfolded protein response kinase PERK supports survival and metastasis of circulating tumor cell clusters via SAM synthesis and H3K4me3‐dependent PDGFB signaling

Cancer Communications, Volume 45, Issue 12, Page 1706-1733, December 2025.
Abstract Background Metastasis is the leading cause of cancer‐related mortality, with circulating tumor cell (CTC) clusters serving as highly efficient precursors of distant metastasis. Survival of CTC clusters in the bloodstream is the primary contributor to tumor metastasis.
Rui Tang, Yan Sun, Ao Deng, Jiahe Liu, Peijin Dai, Jing Chen, Chaoqun Deng, Hui Liu, Yuhang Hai, Yanran Tong, Yan‐e Du, Manran Liu, Haojun Luo   +12 more
wiley   +1 more source

Transcriptomic and proteomic profiling shows dysregulated immune and metabolic pathways in arrhythmogenic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 6, Page 4419-4430, December 2025.
Abstract Aims Arrhythmogenic cardiomyopathy (ACM) is a hereditary heart disease characterized by fibrofatty myocardial replacement and a predisposition to malignant ventricular arrhythmias. The underlying pathomechanisms remain incompletely understood, and specific disease markers are sparse.
Deniz Akdis, Lukas Weidmann, Paolo Nanni, Anna Gaertner, Hendrik Milting, Peter Bode, Corinna Brunckhorst, Liang Chen, Felix C. Tanner, Frank Ruschitzka, Ardan M. Saguner, Firat Duru   +11 more
wiley   +1 more source

The cell-cell junctions of mammalian testes: I. The adhering junctions of the seminiferous epithelium represent special differentiation structures [PDF]

, 2014
The seminiferous tubules and the excurrent ducts of the mammalian testis are physiologically separated from the mesenchymal tissues and the blood and lymph system by a special structural barrier to paracellular translocations of molecules and particles ...
Domke, Lisa M., Dörflinger, Yvette, Franke, Werner W., Heid, Hans, Kuhn, Caecilia, Rickelt, Steffen, Rosin-Arbesfeld, Rina, Winter-Simanowski, Stefanie, Zimbelmann, Ralf   +8 more
core   +2 more sources

Mechanisms That Prevent Vascular Leakage During Leukocyte Extravasation

Acta Physiologica, Volume 241, Issue 12, December 2025.
ABSTRACT Background Inflammation is the response of the immune system against harmful stimuli in tissues. Leukocyte extravasation or TransEndothelial Migration (TEM) is a crucial step during inflammation, in which leukocytes migrate over the endothelial barrier toward the damaged tissue.
Siem J. de Haan, Jaap D. van Buul
wiley   +1 more source

LY6/PLAUR domain containing 3 (LYPD3) maintains melanoma cell stemness and mediates an immunosuppressive microenvironment

Biology Direct, 2023
Background Malignant melanoma is a highly heterogeneous skin cancer with the highest mortality rate among dermatological cancers. Catenins form functional networks in the nucleus to regulate gene expression and determine cell fate.
Yi-dou Hu, Ke Wu, Yuan-jie Liu, Qian Zhang, Hui Shen, Jin Ji, Dong Fang, Song-yang Xi   +7 more
doaj   +1 more source

The Dystrophin Node as Integrator of Cytoskeletal Organization, Lateral Force Transmission, Fiber Stability and Cellular Signaling in Skeletal Muscle

Proteomes, 2021
The systematic bioanalytical characterization of the protein product of the DMD gene, which is defective in the pediatric disorder Duchenne muscular dystrophy, led to the discovery of the membrane cytoskeletal protein dystrophin.
Paul Dowling, Stephen Gargan, Sandra Murphy, Margit Zweyer, Hemmen Sabir, Dieter Swandulla, Kay Ohlendieck   +6 more
doaj   +1 more source

Novel compound mutations in the mitochondrial translation elongation factor (TSFM) gene cause severe cardiomyopathy with myocardial fibro-adipose replacement [PDF]

, 2019
Primary mitochondrial dysfunction is an under-appreciated cause of cardiomyopathy, especially when cardiac symptoms are the unique or prevalent manifestation of disease.
Bonnen, Penelope E, Carbo, Miriam, Cerbelli, Bruna, D'Amati, Giulia, Della Monica, Paola Lilla, Falkous, Gavin, Giordano, Carla, Glasgow, Ruth I C, Hardy, Steven A, He, Langping, Morea, Veronica, Perli, Elena, Pignataro, Maria Gemma, Pisano, Annalinda, Re, Federica, Taylor, Robert W, Zacara, Elisabetta   +16 more
core   +2 more sources