Results 121 to 130 of about 9,234,681 (308)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
River Tavy SAP Final Plan [PDF]
, 2000 This is the River Tavy Salmon Action Plan Final document produced by the Environment Agency in 2000. This final Salmon Action Plan (SAP) for the River Tavy catchment has been produced after consideration of feedback from external consultation.
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
, 2015 The word plan is in English both a verb and a noun, reminding us that to plan is a process resulting in a product, a plan. While the Last Planner System (LPS) is primarily focused on how to plan and control production, other planning concepts are more
Aslesen, Sigmund +2 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Journal for ImmunoTherapy of CancerBackground Owing to their roles in promoting T cell and natural killer (NK) cell activation and proliferation, interleukins-2 (IL-2) and interleukins-15 (IL-15) have been pursued as promising pathways to target in cancer immunotherapy. Nonetheless, their
Camilla Jandus +13 more
doaj +1 more source
, 2015 I was walking on campus today, backpack tight against my shoulders, one headphone in my ear, phone in my back pocket, when I saw a poster calling me a baby killer ...
Anonymous,
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What Does Your Plan Say? Working to Develop a Model Suicide Prevention Plan [PDF]
, 2015 In this article, Dr.
Oliver, Brandie M.
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source