Results 101 to 110 of about 1,588,042 (310)
Le travail dans le champ de la formation des enseignants se numérise et l’accès facilité aux intelligences artificielles génératives ouvrent de nouveaux possibles.
Gaëlle Martin +4 more
doaj +1 more source
L’enseignement des arts visuels, quelles représentations ? :: l’enseignement des arts visuels chez les enseignants de 7 – 8H [PDF]
Selon le Plan d’études romand – PER – (2012), la discipline des arts visuels fait partie intégrante du Plan d’études romand. Les directives demandent aux enseignants de 7 – 8H d’en dispenser une période hebdomadaire.
Baume, Charline, Daucourt, Muriel
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
APPORTS ET DIFFICULTES DE MISE EN PLACE D'UN SYSTEME DE TUTORAT DANS UNE BANQUE REGIONALE
A tutorial system allows experienced employees to develop the competencies of new recruits or internal transfers. Yet, field observations point out difficulties in the implementation of this tool.
Marouby, David, Roger, Alain
core +1 more source
La educación de adultos en el marco universitario: los planes de formación de padres [PDF]
[Resumen] El vertiginoso avance de la sociedad implica la necesidad de articular mecanismos que permitan una adaptación más adecuada de los ciudadanos a las nuevas exigencias sociales.
Díaz Rincón, Begoña +3 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Nestinþ cells direct inflammatory cell migration in atherosclerosis [PDF]
Atherosclerosis is a leading death cause. Endothelial and smooth muscle cells participate in atherogenesis, but it is unclear whether other mesenchymal cells contribute to this process. Bone marrow (BM) nestinþ cells cooperate with endothelial cells in
Andrés, Vicente +6 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Recommandations du groupe de travail urfist [PDF]
Ce rapport présente les conclusions d\u27un groupe de travail présidé par Pierre Carbone, inspecteur général des bibliothèques, sur l\u27évolution du réseau des Unités régionales de formation à l\u27information scientifique et technique (URFIST) dans ...
Carbone, Pierre
core
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source

