Results 11 to 20 of about 10,466 (207)
Nature Communications, 2023 Any planarian fragment regenerates the missing head and tail in the proper end. Early activation of the Wnt/β-catenin signaling pathway changes the chromatin accessibility of the cells of the posterior-facing wound to regenerate a tail.
Eudald Pascual-Carreras +9 more
semanticscholar +1 more source
Nature Communications, 2023 Whole-body regeneration of planarians is a natural wonder but how it occurs remains elusive. It requires coordinated responses from each cell in the remaining tissue with spatial awareness to regenerate new cells and missing body parts.
Guanshen Cui +12 more
semanticscholar +1 more source
Fate specification is spatially intermingled across planarian stem cells
Nature Communications, 2023 Regeneration requires mechanisms for producing a wide array of cell types. Neoblasts are stem cells in the planarian Schmidtea mediterranea that undergo fate specification to produce over 125 adult cell types.
Chanyoung Park +3 more
semanticscholar +1 more source
bioRxiv, 2023 The planarian Schmidtea mediterranea can regenerate its entire body from small tissue fragments and is studied as regeneration model species. The assembly and functional analysis of planarian genomes has proven challenging due its high A/T content (70% A/
Mario Ivanković +17 more
semanticscholar +1 more source
m6A promotes planarian regeneration
Cell Proliferation, 2023 Regeneration is the regrowth of damaged tissues or organs, a vital process in response to damages from primitive organisms to higher mammals. Planarian possesses active whole‐body regenerative capability owing to its vast reservoir of adult stem cells ...
Guanshen Cui +16 more
semanticscholar +1 more source
Frontiers in Molecular Neuroscience, 2022 Disturbances in the excitatory/inhibitory balance of brain neural circuits are the main source of encephalopathy during neurodevelopment. Changes in the function of neural circuits can lead to depolarization or repeat rhythmic firing of neurons in a ...
Hui Zhen +8 more
doaj +1 more source
The known, unknown, and unknown unknowns of cell-cell communication in planarian regeneration
Zoological Research, 2023 Planarians represent the most primitive bilateral triploblastic animals. Most planarian species exhibit mechanisms for whole-body regeneration, exemplified by the regeneration of their cephalic ganglion after complete excision.
Jiajia Chen, Kai Lei
semanticscholar +1 more source
Can Theta Burst Electromagnetic Fields Disrupt Learning in Planaria? Evidence of Impaired Fear-Conditioned Responses. [PDF]
BioelectromagneticsABSTRACT This study explored the impact of low‐intensity theta burst patterned electromagnetic fields (TBEMF) on fear‐related learning in the flatworm species Planaria, a simple model organism known for its regenerative properties and ability to demonstrate basic learning behaviors. Planaria were exposed to an aversive stimulus (light) in a T‐maze, and
Ghassemkhani K, Dotta BT.
europepmc +2 more sources
Island-specific evolution of a sex-primed autosome in a sexual planarian
Nature, 2022 The sexual strain of the planarian Schmidtea mediterranea, indigenous to Tunisia and several Mediterranean islands, is a hermaphrodite1,2. Here we isolate individual chromosomes and use sequencing, Hi-C3,4 and linkage mapping to assemble a chromosome ...
Longhua Guo +15 more
semanticscholar +1 more source
The planarian wound epidermis gene equinox is required for blastema formation in regeneration
Nature Communications, 2022 Regeneration often involves the formation of a blastema, an outgrowth or regenerative bud formed at the plane of injury where missing tissues are produced. The mechanisms that trigger blastema formation are therefore fundamental for regeneration.
M. L. Scimone +3 more
semanticscholar +1 more source