Results 21 to 30 of about 10,466 (207)

m6A is required for resolving progenitor identity during planarian stem cell differentiation

EMBO Journal, 2022
Regeneration and tissue homeostasis require accurate production of missing cell lineages. Cell production is driven by changes to gene expression, which is shaped by multiple layers of regulation. Here, we find that the ubiquitous mRNA base‐modification,
Y. Dagan, Yarden Yesharim, Ashley R. Bonneau, Tamar Frankovits, Schraga Schwartz, P. Reddien, O. Wurtzel   +6 more
semanticscholar   +1 more source

An insight into planarian regeneration

Cell Proliferation, 2022
Planarian has attracted increasing attentions in the regeneration field for its usefulness as an important biological model organism attributing to its strong regeneration ability.
Xin-Yang Ge, Xiao Han, Yong‐Liang Zhao, Guanshen Cui, Yun-Gui Yang   +4 more
semanticscholar   +1 more source

Spontaneous Behaviors and Wall-Curvature Lead to Apparent Wall Preference in Planarian. [PDF]

PLoS ONE, 2015
The planarian Dugesia japonica tends to stay near the walls of its breeding containers and experimental dishes in the laboratory, a phenomenon called "wall preference". This behavior is thought to be important for environmental adaptation, such as hiding
Yoshitaro Akiyama, Kiyokazu Agata, Takeshi Inoue   +2 more
doaj   +1 more source

Identification of putative enhancer-like elements predicts regulatory networks active in planarian adult stem cells

bioRxiv, 2022
Planarians have become an established model system to study regeneration and stem cells, but the regulatory elements in the genome remain almost entirely undescribed. Here, by integrating epigenetic and expression data we use multiple sources of evidence
Jakke Neiro, Divya Sridhar, Anish Dattani, A. Aboobaker   +3 more
semanticscholar   +1 more source

Finding the potency in planarians

Communications Biology, 2022
Recent developments in the field of planarian stem cell research are discussed, an active and accessible stem cell system that can generate any cell type of the planarian body, to address the question of pluripotency among neoblasts.
Bret J. Pearson
doaj   +1 more source

Planarian nociception: Lessons from a scrunching flatworm

Frontiers in Molecular Neuroscience, 2022
In addition to being studied for their exceptional regeneration abilities, planarians (i.e., flatworms) have also been extensively used in the context of pharmacological experiments during the past century.
Guillaume Reho, V. Lelièvre, H. Cadiou
semanticscholar   +1 more source

Toxicity of ceria nanoparticles to the regeneration of freshwater planarian Dugesia japonica: The role of biotransformation.

Science of the Total Environment, 2022
Cerium oxide nanoparticles (n-CeO2) have wide applications ranging from industrial to consumer products, which would inevitably lead to their release into the environment.
Changjiang Xie, Xiaowei Li, L. Hei, Yiqing Chen, Yuling Dong, Shujing Zhang, Shan Ma, Jianing Xu, Qiuxiang Pang, I. Lynch, Zhiling Guo, P. Zhang   +11 more
semanticscholar   +1 more source

Neuronal sources of hedgehog modulate neurogenesis in the adult planarian brain

eLife, 2016
The asexual freshwater planarian is a constitutive adult, whose central nervous system (CNS) is in a state of constant homeostatic neurogenesis. However, very little is known about the extrinsic signals that act on planarian stem cells to modulate rates ...
Ko W Currie, Alyssa M Molinaro, Bret J Pearson   +2 more
doaj   +1 more source

Eco(toxicological) Assessment of the Neonicotinoid Formulation Actara® Using Planarian Girardia tigrina as Model Organism

Pollutants, 2022
Neonicotinoid pesticides are one of the most commercialized groups worldwide. Their application in agriculture aims to control pests through a systemic mode of action which is not specific to target species. Our study aimed to evaluate the effects of the
Rone S. Barbosa, Eliane Aparecida Rotili, Amanda Magda Almeida Santos, Fabianne Ribeiro, A. Dornelas, D. Pereira, G. Cavallini, A. Soares, R. Sarmento, C. Gravato   +9 more
semanticscholar   +1 more source

Gene Delivery System Using Droplet Injector and Temperature-Controlled Planarian Holder

Inventions, 2018
A microinjection system for gene delivery to a planarian was presented with materials widely used by manufacturers. The system consists of a nanoliter droplet generator/injector and a planarian holder.
Michael Lee, Jing-Jie Syu, Chia-Ying Chu, Yen-Wen Lu   +3 more
doaj   +1 more source