Results 51 to 60 of about 10,466 (207)

FoxK1 is Required for Ectodermal Cell Differentiation During Planarian Regeneration

open access: yesFrontiers in Cell and Developmental Biology, 2022
Forkhead box (Fox) genes belong to the “winged helix” transcription factor superfamily. The function of some Fox genes is well known, such as the role of foxO in controlling metabolism and longevity and foxA in controlling differentiation of endodermal ...
Pablo Coronel-Córdoba   +15 more
doaj   +1 more source

WNT-FRIZZLED-LRP5/6 Signaling Mediates Posterior Fate and Proliferation during Planarian Regeneration

open access: yesGenes, 2021
An organizer is defined as a group of cells that secrete extracellular proteins that specify the fate of surrounding cells according to their concentration. Their function during embryogenesis is key in patterning new growing tissues. Although organizers
Eudald Pascual-Carreras   +7 more
semanticscholar   +1 more source

Cell-type diversity and regionalized gene expression in the planarian intestine

open access: yeseLife, 2020
Proper function and repair of the digestive system are vital to most animals. Deciphering the mechanisms involved in these processes requires an atlas of gene expression and cell types.
David J. Forsthoefel   +3 more
semanticscholar   +1 more source

RNAi Screen of RING/U-Box Domain Ubiquitin Ligases Identifies Critical Regulators of Tissue Regeneration in Planarians

open access: yesFrontiers in Cell and Developmental Biology, 2022
Regenerative processes depend on the interpretation of signals to coordinate cell behaviors. The role of ubiquitin-mediated signaling is known to be important in many cellular and biological contexts, but its role in regeneration is not well understood ...
John M. Allen   +8 more
doaj   +1 more source

Muscle and neuronal guidepost-like cells facilitate planarian visual system regeneration

open access: yesScience, 2020
Guiding regeneration Many adult organisms can regenerate neural circuits after injury. However, it is not clear which guidance mechanisms operate to promote axon path finding in the adult. Scimone et al.
M. L. Scimone   +5 more
semanticscholar   +1 more source

Fatty Acid Content and Composition of Freshwater Planaria Dendrocoelopsis sp. (Planariidae, Turbellaria, Platyhelminthes) from the Yenisei River [PDF]

open access: yesЖурнал Сибирского федерального университета: Серия Биология, 2009
For the first time the fatty acid content and composition of freshwater planarian Dendrocoelopsis sp. has been studied in a station of the large Siberian River, the Yenisei.
Olesia N. Makhutova   +3 more
doaj  

Downregulation of mTOR Signaling Increases Stem Cell Population Telomere Length during Starvation of Immortal Planarians

open access: yesStem Cell Reports, 2019
Summary: Reduction of caloric intake delays and prevents age-associated diseases and extends the life span in many organisms. It may be that these benefits are due to positive effects of caloric restriction on stem cell function.
Marta Iglesias   +9 more
doaj   +1 more source

Dugesia japonica is the best suited of three planarian species for high-throughput toxicology screening

open access: yesbioRxiv, 2020
High-throughput screening (HTS) using new approach methods is revolutionizing toxicology. Asexual freshwater planarians are a promising invertebrate model for neurotoxicity HTS because their diverse behaviors can be used as quantitative readouts of ...
D. Ireland   +6 more
semanticscholar   +1 more source

Why we age

open access: yesBiological Reviews, EarlyView.
ABSTRACT Three categories of explanations exist for why we age: mechanistic theories, which omit reference to evolutionary forces; weakening force of selection theories, which posit that barriers exist that prevent evolutionary forces from optimising fitness in ageing; and optimisation theories, which posit that evolutionary forces actually select for ...
Michael S. Ringel
wiley   +1 more source

Studying Planarian Regeneration Aboard the International Space Station Within the Student Space Flight Experimental Program

open access: yesFrontiers in Astronomy and Space Sciences, 2018
The growing possibilities of space travel are quickly moving from science fiction to reality. However, to realize the dream of long-term space travel, we must understand how these conditions affect biological and physiological processes.
Vista SSEP Mission 11 Team   +5 more
doaj   +1 more source

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