Results 71 to 80 of about 10,466 (207)

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney   +4 more
wiley   +1 more source

Inhibitory Effects of Antiparkinsonian Drugs and Caspase Inhibitors in a Parkinsonian Flatworm Model

open access: yesJournal of Pharmacological Sciences, 2003
It has been known that rotenone and 1-methyl-4-phenylpyridinium ion (MPP+, a metabolite of MPTP), which inhibit mitochondrial complex I, are useful tools for parkinsonian models in vertebrates such as primates and rodents.
Yoshihisa Kitamura   +9 more
doaj   +1 more source

Fraternal cooperation of hierarchical cancer parallels metazoan multicellularity and eusociality

open access: yesBiological Reviews, Volume 101, Issue 1, Page 400-418, February 2026.
ABSTRACT Metazoan multicellularity and eusociality — both outcomes of the fraternal major transitions — have numerous features in common such as uneven distribution of group‐establishing potential. In addition to this framework, I argue herein that the group‐forming principles of metazoan multicellularity and eusociality are analogous to hierarchical ...
Jibeom Choi
wiley   +1 more source

Aging as a Loss of Goal‐Directedness: An Evolutionary Simulation and Analysis Unifying Regeneration with Anatomical Rejuvenation

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
The paper proposes that the root cause of aging is the loss of anatomical goal‐directedness after development. Using evolutionary neural cellular automata simulations, the authors show that after the organism has reached its developmental homeostatic setpoint (the adult morphology), the absence of target state to pursue leads to a drifting anatomical ...
Léo Pio‐Lopez   +2 more
wiley   +1 more source

Crosslinked Poly(Acrylic Acid‐Co‐Acrylamide) Applied to Remove Hg(II) and the Effects of Its Exposure on Girardia tigrina

open access: yesPolymer Engineering &Science, Volume 65, Issue 12, Page 6964-6979, December 2025.
The polymeric adsorption of Hg(II) and the assessment of ecotoxicity. ABSTRACT In this study, an adsorbent was produced by the copolymerization of acrylic acid and acrylamide, followed by cross‐linking. The impact of pH, duration of contact, concentration, presence of interfering ions, and reuse was investigated.
Roberta Brito Vasconcelos   +4 more
wiley   +1 more source

Draft genome of Metabacillus niabensis strain 4T19T isolated from cotton-waste composts for mushroom cultivation

open access: yesNew Microbes and New Infections, 2021
In this article, we present the draft genome sequence of Metabacillus niabensis strain 4T19T (= CSUR Q2603 T = DSM 17723 = JCM 16399 = KACC 11279), that is a new Metabacillus species isolated from cotton-waste composts.
L.J. Kangale   +4 more
doaj   +1 more source

Cell lineage tracing: Methods, applications, and challenges

open access: yesQuantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cell lineage tracing is a crucial technique for understanding cell fate and lineage relationships, with wide applications in developmental biology, tissue regeneration, and disease progression studies. Over the years, experimental cell lineage tracing methods have advanced from early labeling techniques to modern genetic tools such as CRISPR ...
Shanjun Mao   +5 more
wiley   +1 more source

Physiological evaluation of the behavior and epidermis of freshwater planarians (Girardia tigrina and Girardia sp.) exposed to stressors

open access: yesBiology Open, 2018
Planarians are metazoan freshwater flatworms which are free-living organisms. Their body has pluripotent stem cell promoters of tissue regeneration capacity.
Matheus Salgado de Oliveira   +4 more
doaj   +1 more source

Differences in neurotoxic outcomes of organophosphorus pesticides revealed via multi-dimensional screening in adult and regenerating planarians

open access: yesFrontiers in Toxicology, 2022
Organophosphorus pesticides (OPs) are a chemically diverse class of commonly used insecticides. Epidemiological studies suggest that low dose chronic prenatal and infant exposures can lead to life-long neurological damage and behavioral disorders.
Danielle Ireland   +11 more
doaj   +1 more source

Orthogonal muscle fibers have different instructive roles in planarian regeneration

open access: yesNature, 2017
The ability to regenerate missing body parts exists throughout the animal kingdom. Positional information is crucial for regeneration, but how it is harboured and used by differentiated tissues is poorly understood.
M. L. Scimone   +2 more
semanticscholar   +1 more source

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