Results 81 to 90 of about 82,884 (244)

Facial [r,s,t]-Colorings of Plane Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2019
Let G be a plane graph. Two edges are facially adjacent in G if they are consecutive edges on the boundary walk of a face of G. Given nonnegative integers r, s, and t, a facial [r, s, t]-coloring of a plane graph G = (V,E) is a mapping f : V ∪ E → {1, . .
Czap Július   +3 more
doaj   +1 more source

Which point sets admit a $k$-angulation?

open access: yesJournal of Computational Geometry, 2014
For \(k\ge 3\), a \(k\)-angulation is a 2-connected plane graph in which every internal face is a \(k\)-gon. We say that a point set \(P\) admits a plane graph \(G\) if there is a straight-line drawing of \(G\) that maps \(V(G)\) onto \(P\) and has the ...
Michael S. Payne   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

An Extension of Kotzig’s Theorem

open access: yesDiscussiones Mathematicae Graph Theory, 2016
In 1955, Kotzig proved that every 3-connected planar graph has an edge with the degree sum of its end vertices at most 13, which is tight. An edge uv is of type (i, j) if d(u) ≤ i and d(v) ≤ j.
Aksenov Valerii A.   +2 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Odd facial total-coloring of unicyclic plane graphs [PDF]

open access: yesDiscrete Mathematics Letters, 2022
Július Czap
doaj   +1 more source

Galois connections between sets of paths and closure operators in simple graphs

open access: yesOpen Mathematics, 2018
For every positive integer n,we introduce and discuss an isotone Galois connection between the sets of paths of lengths n in a simple graph and the closure operators on the (vertex set of the) graph.
Šlapal Josef
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Rainbowness of plane graphs

open access: yesElectronic Notes in Discrete Mathematics, 2007
Abstract The rainbowness, rb ( G ) , of a connected plane graph G is the minimum number k such that any colouring of vertices of the graph G using at least k colours involves a face all vertices of which receive distinct colours. We give a survey on recent results concerning ranbowness of plane graphs.
openaire   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

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