Results 71 to 80 of about 7,142,404 (288)

Reformulation in planning [PDF]

open access: yes, 2002
Reformulation of a problem is intended to make the problem more amenable to efficient solution. This is equally true in the special case of reformulating a planning problem.
A. Gerevini   +6 more
core   +3 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

PARTICULARITIES OF MANAGEMENT FUNCTIONS IN PUBLIC PROCUREMENT PROCESSES IN ROMANIA [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2019
The public procurement system contains all the rules to be respected in relation to the use of funds coming from the state budget / local budgets in which requests for procurement of products, services or works of different contracting authorities meet
PREDA IONEL
doaj  

Strategizing as a New Field of Professional Knowledge

open access: yesУправленческое консультирование, 2018
The article proves the necessity of singling out the strategy as an independent field of economic knowledge in the professional sphere of activity. In Russia, there is practically no fullfledged perception of the “strategist” profession, although in the
Murad Kamilovich Alimuradov   +1 more
doaj   +1 more source

UCL (University College London) Libraries Masterplan: Library Report to Estates Management Committee January 2008 [PDF]

open access: yes, 2008
This document is a Report from UCL Library Services to UCL on Master Planning activities and outputs which have been undertaken to quantify use and development of estate in UCL Library Services.
Ayris, P.   +1 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Reinforcement learning based two‐timescale energy management for energy hub

open access: yesIET Renewable Power Generation
Maintaining energy balance and economical operation is significant for energy hub (EH) which serves as the central component. Implementing real‐time regulation for heating and cooling equipment within the EH is challenging due to their slow response time
Jinfan Chen   +8 more
doaj   +1 more source

Los residuos generados por la industria extractiva: virtudes y deficiencias del marco regulador

open access: yesRevista Vasca de Administración Pública, 2012
The recent reform of the Royal Decree on waste management and rehabilitation of areas affected by mining has highlighted the importance of the environmental perspective in extractive activities.
M.ª Remedios Zamora Roselló
doaj   +1 more source

SUSTAINABLE DEVELOPMENT OF REGIONAL TOURISM [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2012
Development of tourism as an economic branch meets all requirements of sustainable development considering that can be touched all three pillars of this type of development: economic development, social development, environmental protection.
NEAMŢU ADINA CLAUDIA, NEAMŢU LIVIU
doaj  

Cooperative Epistemic Multi-Agent Planning for Implicit Coordination [PDF]

open access: yes, 2017
Epistemic planning can be used for decision making in multi-agent situations with distributed knowledge and capabilities. Recently, Dynamic Epistemic Logic (DEL) has been shown to provide a very natural and expressive framework for epistemic planning. We
Bolander, Thomas   +3 more
core   +2 more sources

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