Results 41 to 50 of about 377,633 (266)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Eight heuristic planning techniques applied to three increasingly difficult wildlife planning problems

Silva Fennica, 2002
As both spatial and temporal characteristics of desired future conditions are becoming important measures of forest plan success, forest plans and forest planning goals are becoming complex.
Bettinger, Pete, Graetz, David, Boston, Kevin, Sessions, John, Chung, Woodam   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The Altadir Method of Popular Planning as a management teaching instrument in nursing El método Altadir de planificación popular como instrumento de enseñanza de la gestión en enfermería O Método Altadir de Planificação Popular como instrumento de ensino da gerência em enfermagem

Investigación y Educación en Enfermería, 2012
This paper presents the Altadir Method of Popular Planning (MAPP), which is considered an effective tool for nursing management teaching and learning.
Vanessa Denardi Antoniassi Baldissera, Herbert Leopoldo de Freitas Góes   +1 more
doaj  

National growth models for stand basal area, volume, and biomass in Chinese larch plantations: integrating stand structure and species effects

Trees, Forests and People
Forest growth and yield models are essential tools for forest management decision-making, but most models have neglected the inclusion of stand structure. The relationship between stand structure and stand growth has been widely reported, but the results
Yangping Qin, Xiao He, Hong Guo, Chaofan Zhou, Weisheng Zeng, Xinyun Chen, Xiangdong Lei   +6 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Planificación familiar en mujeres en condiciones de vulnerabilidad social Family planning for women in vulnerable social

Salud UIS, 2011
Introducción: La planificación familiar es un componente esencial en el cuidado de la salud primaria y reproductiva desatendida en poblaciones socialmente vulnerables.
Liliana Franco Hincapié, Gabriela María Mora Zapata, Ana Lucía Mosquera Hinestroza, Víctor Daniel Calvo Betancur   +3 more
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Benchmarking energy consumption and solar energy potential for sustainable photovoltaic integration in university campus buildings

Scientific Reports
Integrating photovoltaic (PV) technologies has emerged as a crucial strategy to address Algeria’s energy, economic, and environmental challenges. Urgent solutions are needed with growing energy demand and limited renewable energy adoption.
Amina Bekkouche, Fatiha Benidir, Abdelhak Lekbir, Abdullahi Mohamed Samatar, Saad Mekhilef   +4 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source