Results 21 to 30 of about 377,633 (266)

Techniques of Learning Planning Patterns Character Digitalization_Literacy 4.0

open access: yesJurnal Mangifera Edu, 2022
Careful learning planning is important because if it is not prepared it will make the system less controlled. Learning planning must be adjusted to the quality and vision of the university and the demands for accreditation of study programs 4.0 ...
Eka Vasia Anggis, Nur Laili
doaj   +1 more source

Comprehensive Review on Climate Control and Cooling Systems in Greenhouses under Hot and Arid Conditions

open access: yesAgronomy, 2022
This work is motivated by the difficulty of cultivating crops in horticulture greenhouses under hot and arid climate conditions. The main challenge is to provide a suitable greenhouse indoor environment, with sufficiently low costs and low environmental ...
Meriem Soussi   +3 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Evaluating Privacy-Level Metrics in Privacy-Preserving Data Mining [PDF]

open access: yesInternational Journal of Intelligent Computing and Information Sciences
The increasing collection and analysis of sensitive personal data necessitates the development of robust Privacy-Preserving Data Mining (PPDM) methods. PPDM techniques are essential for extracting valuable insights from sensitive data while ensuring the ...
Alshaimaa Abo-alian   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Analysis of Computer Aided Process Planning Techniques

open access: yesTikrit Journal of Engineering Sciences, 2009
Computer Aided Process Planning ( CAPP) has been recognized as playing a key role in Computer Integrated Manufacturing ( CIM ). It was used as a bridge to link CAD with CAM systems, in order to give the possibility of full integration in agreement with ...
Salim A. Saleh
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

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