The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
The rise of plant-based milk alternatives: exploring nutritional, health, and sustainability impacts. [PDF]
Asif N +7 more
europepmc +1 more source
Analysis of Eight Types of Plant-based Milk Alternatives from the United States Market for Target Minerals and Trace Elements. [PDF]
Redan BW +6 more
europepmc +1 more source
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang +16 more
wiley +1 more source
Characterization of Metabolites in Plant-Based Milk Yogurt Enriched with <i>Wolffia globosa</i> to Improve Bionutritional and Functional Properties. [PDF]
Punyauppa-Path S +7 more
europepmc +1 more source
Enzyme immunoassays for the detection of mycotoxins in plant-based milk alternatives: pitfalls and limitations. [PDF]
Rehagel C +3 more
europepmc +1 more source
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao +21 more
wiley +1 more source
Characterization of Plant-Based Milk-Derived "Fujiharu Butter": Comparison With Butter and Butter-Like Substitutes. [PDF]
Kazama R +8 more
europepmc +1 more source
Perceptions toward Plant-Based Milk Alternatives among Young Adult Consumers and Non-Consumers in Denmark: An Exploratory Study. [PDF]
Martínez-Padilla E +3 more
europepmc +1 more source
Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley +1 more source

