Results 51 to 60 of about 6,054,770 (234)

In Vivo Imaging for the Visualization of Extracellular Vesicle‐Based Tumor Therapy

ChemistryOpen, 2022
Extracellular vesicles (EVs) exhibiting versatile biological functions provide promising prospects as natural therapeutic agents and drug delivery vehicles. For future clinical translation, revealing the fate of EVs in vivo, especially their accumulation
Anqi Jiang, Prof. Dr. Weidong Nie, Prof. Dr. Hai‐Yan Xie   +2 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Characterization of human islet-derived EVs.

, 2014
A) Nanosight analysis of 10 k and 100 k fraction EVs. In Nanosight analysis, curve 1 describes the relationship between particle number distribution (left Y axis) and particle size (X axis); curve 2 describes the correlation between cumulative percentage
Michela De Lena (598990), Renato Romagnoli (598992), Raffaella Melzi (249815), Mauro Salizzoni (598993), Silvia Beltramo (598991), Lorenzo Piemonti (249842), Federico Figliolini (598989), Luigi Biancone (92819), Giovanni Camussi (92821), Ciro Tetta (245012), Rita Nano (598994), Vincenzo Cantaluppi (92814)   +11 more
core   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

EVS: Head-up or Head Down? Evaluation of Crew Procedure and Human Factors for Enhanced Vision Systems [PDF]

, 2009
Feasibility of an EVS head-down procedure is examined that may provide the same operational benefits under low visibility as the FAA rule on Enhanced Flight Visibility that requires the use of a head-up display (HUD).
Lenz, H, Korn, B, Biella, M, Schmerwitz, S   +3 more
core  

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Plant Roots Release Small Extracellular Vesicles with Antifungal Activity

, 2020
Extracellular Vesicles (EVs) play pivotal roles in cell-to-cell and inter-kingdom communication. Despite their relevant biological implications, the existence and role of plant EVs released into the environment has been unexplored.
Antonietta Leone, Ramesh Bokka, Lilla Turiák, Gabriella Pocsfalvi, Alfredo Ambrosone, Pasquale Del Gaudio, Immacolata Fiume, Michelina Ruocco, Marina Tucci, Monica De Palma   +9 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

The Potentiality of Plant-Derived Nanovesicles in Human Health—A Comparison with Human Exosomes and Artificial Nanoparticles

, 2022
Research in science and medicine is witnessing a massive increases in literature concerning extracellular vesicles (EVs). From a morphological point of view, EVs include extracellular vesicles of a micro and nano sizes.
Stefano Fais, Logozzi, Mariantonia, Di Raimo, Rossella, Fais, Stefano, Rossella Di Raimo, Mariantonia Logozzi, Davide Mizzoni, Mizzoni, Davide   +7 more
core   +1 more source