Results 121 to 130 of about 6,054,169 (340)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Sulfonamine-containing aurone derivatives act as inhibitors of intercellular movement of potato virus Y

iScience
Summary: Intercellular movement plays an important role in plant virus infection and transmission, which provides an opportunity for antiviral agents that interfere with the intercellular motion.
Dan Chen, Qingqing Ma, Xin Li, Tao Yang, Shang Wu, Yanju Wang, Deyu Hu   +6 more
doaj   +1 more source

Sphagnum physiology in the context of changing climate: emergent influences of genomics, modelling and host-microbiome interactions on understanding ecosystem function. [PDF]

, 2014
Peatlands harbour more than one-third of terrestrial carbon leading to the argument that the bryophytes, as major components of peatland ecosystems, store more organic carbon in soils than any other collective plant taxa. Plants of the genus Sphagnum are
Gu, Lianhong, Muchero, Wellington, Schmutz, Jeremy, Shaw, A Jonathan, Timm, Collin M, Tuskan, Gerald A, Walker, Anthony P, Warren, Jeffrey M, Weston, David J, Wullschleger, Stan D   +9 more
core   +1 more source

Thermodynamical journey in plant biology

Frontiers in Plant Science, 2015
Nonequilibrium irreversible thermodynamics constitute a meaningful point of view suitable to explore life with a rich paradigm. This analytical framework can be used to span the gap from molecular processes to plant function and shows great promise to ...
Adelin Barbacci, V. Magnenet, M. Lahaye
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Genome-wide analysis of flax bZIP genes using a T2T genome reveals abiotic stress roles

iScience
Summary: The basic leucine zipper (bZIP) transcription factor family plays key roles in plant growth, development, and environmental stress responses but remains poorly characterized in flax (Linum usitatissimum L.).
Hang Wang, Jianyu Lu, Shuyao Li, Jinxi Li, Hanlu Wu, Yifei Wang, Jiahui Yu, Zhengyuan Zang, Ruidong Sun, Michael K. Deyholos, Guangwen Wu, Lifei Chen, Jian Zhang   +12 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Prospects of Agriculture in Iraq in the Face of Climate Change [PDF]

مجلة جامعة الانبار للعلوم الصرفة
In the Middle East and North Africa region, Iraq is considered one of the most vulnerable countries to the impacts of climate change. In recent years, Iraq has witnessed tangible climate changes, including a sharp rise in temperatures, a decline in water
Anmar Alalwani, idrees Mola Salih, Mukhalad Alani, Ahmed Fatkhan Zabar   +3 more
doaj   +1 more source

Considerations for designing chemical screening strategies in plant biology

Frontiers in Plant Science, 2015
Traditionally, biologists regularly used classical genetic approaches to characterize and dissect plant processes. However, this strategy is often impaired by redundancy, lethality or pleiotropy of gene functions, which prevent the isolation of viable ...
M. Serrano, E. Kombrink, C. Meesters
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source