Results 61 to 70 of about 599,263 (289)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
ScientificaThe experiment was conducted using an alpha lattice design with two replications for each genotype, comprising 20 maize hybrids obtained from CIMMYT and NMRP, including two check varieties.
Ram Chandra Bhatta +4 more
doaj +1 more source
Scientific Reports, 2020 Tuber starch content (TSC) is a very important trait in potato (Solanum tuberosum L.). This study is the first to use expression quantitative trait loci (eQTL) mapping of transcript-derived markers for TSC in potato.
Dorota Sołtys-Kalina +5 more
doaj +1 more source
Changing Paradigms in Plant Breeding [PDF]
Plant Physiology, 2001 The origin of plant breeding traces back to the dawn of agriculture and the domestication of plants, when nomadic man first became a settler. This started in those regions of the world where plants suitable for domestication, such as large grain grasses, grew in the wild.
Koornneef, M., Stam, P.
openaire +2 more sources
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Scientific Reports, 2023 Thirteen known Yr gene-associated markers pertaining to genes (Yr5, Yr10, Yr15, Yr24/Yr26) were used to identify the genes in selected wheat germplasm which were found resistant under field conditions at two locations in Punjab, India against stripe rust.
Mohammad Waris Haider +7 more
doaj +1 more source
Participatory Plant Breeding Methods for Organic Cereals [PDF]
, 2005 Formal breeding methods were not always suitable to address the very large diversity of both environmental conditions and end-user needs. Both were frequently encountered either in marginal areas of developing countries or in organic farms of EEC ...
Desclaux, D.
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
New potato variety Virazh with resistance to golden potato nematode
Аграрная наука Евро-Северо-Востока, 2016 Characteristics of mid-early potato variety Virazh (Gloriya x 282-97) which combines high productivity (up to 39.6 t/ha) with resistance to viruses, common pathotype of cancer, golden potato nematode, common scab is presented in the article.
Z. F. Serqeeva +3 more
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source