Results 71 to 80 of about 599,263 (289)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Genome Wide Identification and Characterization of LIM Domain Associated Gene Superfamily in Common Bean (Phaseolus vulgaris L.)

open access: yesInternational Journal of Genomics
LIM genes are essential for cytoskeletal organization and cellular stress responses in plants. This study conducted a comprehensive genome-wide investigation of LIM domain-associated genes in Phaseolus vulgaris. This study expands LIM gene classification
Raiyyan Abdur Rahim   +4 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Combining Ability and Heterosis Analysis in Wheat (Triticum aestivum L.) Under Normal and Terminal Heat Stress Conditions

open access: yesInternational Journal of Agronomy
A study using a (4 × 4) F1 full diallel population of four parents: BARI Gom-25 (P1), BARI Gom-26 (P2), BARI Gom-33 (P3), and Pavan (P4) was conducted following randomized complete block design with three replications under optimum and late sowing ...
Arpan Das   +4 more
doaj   +1 more source

Genetic diversity of barley landraces from Near East, North Africa and Southern Europe in relation to resistance to powdery mildew

open access: yesPlant Protection Science, 2002
This study was conducted to determine the resistance to powdery mildew in 218 barley landraces collected in Near East (Israel, Lebanon, Syria, Turkey, Iran, Iraq), North Africa (Egypt, Algeria, Morocco) and Southern Europe (Greece, Bulgaria, Yugoslavia ...
J.H. Czembor, H.J. Czembor, M. Mackey
doaj   +1 more source

Plant Breeding Goes Microbial

open access: yesTrends in Plant Science, 2017
Plant breeding has traditionally improved traits encoded in the plant genome. Here we propose an alternative framework reaching novel phenotypes by modifying together genomic information and plant-associated microbiota. This concept is made possible by a novel technology that enables the transmission of endophytic microbiota to the next plant ...
Wei, Zhong, Jousset, Alexandre
openaire   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Coordination of shoot apical meristem shape and identity by APETALA2 during floral transition in Arabidopsis

open access: yesNature Communications
Plants flower in response to environmental signals. These signals change the shape and developmental identity of the shoot apical meristem (SAM), causing it to form flowers and inflorescences.
Enric Bertran Garcia de Olalla   +10 more
doaj   +1 more source

Circular 82 [PDF]

open access: yes, 1991
The development of improved plant cultivars is accomplished through comprehensive plant breeding programs. Such programs: 1) evaluate genetically-diverse germplasm in order to identify superior-performing genotypes; 2) create new genetic ...
Blake, Steve A.   +2 more
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