Results 111 to 120 of about 1,261,885 (193)

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Functional Analysis of Mature Activin A Produced by Enterokinase in Plant Cells. [PDF]

Rice (N Y)
Moon KB, Park JS, Kim HG, Jeon JH, Kwon TH, Chung KS, Lee HJ, Kim HS.   +7 more
europepmc   +1 more source

Electrifying rhythms in plant cells. [PDF]

Curr Opin Cell Biol, 2022
Damineli DSC, Portes MT, Feijó JA.
europepmc   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

The roles of movement and coat proteins in the transport of tobamoviruses between plant cells. [PDF]

Front Plant Sci
Kan Y, Citovsky V.
europepmc   +1 more source

Sachihiro Matsunaga: FISHing the nuclear architecture of plant cells. [PDF]

J Cell Biol, 2022
Morgado-Palacin L.
europepmc   +1 more source

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Genome-scale metabolic model led engineering of Nothapodytes nimmoniana plant cells for high camptothecin production. [PDF]

Front Plant Sci, 2023
Murali S, Ibrahim M, Rajendran H, Shagun S, Masakapalli SK, Raman K, Srivastava S.   +6 more
europepmc   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

A novel tobamo-like mycovirus with filamentous particles replicates in plant cells. [PDF]

J Virol
Hong M, Tian F, Song Z, Liu H, Tong Y, Zhang T.   +5 more
europepmc   +1 more source