Results 251 to 260 of about 16,481,877 (361)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

An epigenetic view of plant cells cultured in vitro: somaclonal variation and beyond.

Journal of Experimental Botany, 2011
C. Miguel, L. Marum
semanticscholar   +1 more source

Quantitative dissection of Agrobacterium T-DNA expression in single plant cells reveals density-dependent synergy and antagonism. [PDF]

Nat Plants
Alamos S, Szarzanowicz MJ, Thompson MG, Stevens DM, Kirkpatrick LD, Dee A, Pannu H, Cui R, Liu S, Nimavat M, Krasileva K, Baidoo EEK, Shih PM.   +12 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Expression of bacterial genes in plant cells.

Proceedings of the National Academy of Sciences of the United States of America, 1983
R. Fraley, S. G. Rogers, R. Horsch, P. Sanders, J. Flick, S. Adams, M. Bittner, L. Brand, C. Fink, J. Fry, G. Galluppi, S. Goldberg, N. Hoffmann, S. C. Woo   +13 more
semanticscholar   +1 more source

Abscisic acid enhances DNA damage response through the nuclear shuttling of clathrin light chain 2 in plant cells. [PDF]

Sci Adv
Jiang J, Zhu Q, Li Y, Wu J, Zou C, Li H, Lei X, Zhang F, Lin Y, Cao R, Cao Y, Mo J, Lai J, Zhao J, Wang C, Yang C.   +15 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Correction: Simultaneous quantification of cell wall elasticity and turgor pressure in live plant cells by elastic shell theory analysis and AFM. [PDF]

Planta
Yamasaki Y, Okano K, Mimura T, Tsugawa S, Hosokawa Y.   +4 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity. [PDF]

Front Bioeng Biotechnol
Babu R, Veeramani M, Aadinath W, Muthuvijayan V, Singh S, Srivastava S.   +5 more
europepmc   +1 more source