Results 251 to 260 of about 1,399,282 (308)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Plant Stem Cells

Molecular Biology, 2020
A brief review of current data on the molecular biology of stem cells forming meristems and differentiating into various organs of angiosperms is presented. Different primary and secondary meristems are compared. The interactions of some hormones, regulatory gene networks, and signaling pathways in different types of meristems are described.
A S, Voronina, E S, Pshennikova
openaire   +2 more sources

Immobilized plant cells

Applied Biochemistry and Biotechnology, 1982
Plant cells have been immobilized in alginate, where they have been shown to retain their biological activity. Such systems can be utilized for bioconversions.
P, Brodelius, K, Mosbach
openaire   +3 more sources

The dynamic plant cell

Current Opinion in Plant Biology, 2010
As our cover video illustrates, plant cells are very dynamic; their structure and molecular composition constantly changes as they progress through the cell cycle, divide, differentiate into specialised cell types, and respond to fluctuating environments. Progress in all of these areas is summarized in this issue.
Luschnig, C, Grierson, CS
openaire   +3 more sources

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