Results 121 to 130 of about 442,874 (256)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Editorial: Pathogen co-infections and plant diseases. [PDF]

open access: yesFront Microbiol, 2023
Zhou J, Kolb S, Zhou X.
europepmc   +1 more source

Soil-borne diseases and their role in plant propagation

open access: yes, 1977
The effects of four genera of fungal plant pathogens on seedlings and cuttings are reviewed.
McCully, A. J., Thomas, Michael B.
core  

Potential of biocontrol for the sustainable management of plant diseases in Scotland: Opportunities and barriers

open access: yes
Previous PHC projects identified biocontrol as a major element of Integrated Pest Management (IPM) with a role to play in mitigating pesticide withdrawals.
Creissen, Henry   +4 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Mycotoxins and plant diseases in a changing climate: from pathogen ecology to smart surveillance and mitigation strategies. [PDF]

open access: yesFront Fungal Biol
Dehbi I   +9 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Distributed Deep Learning in IoT Sensor Network for the Diagnosis of Plant Diseases. [PDF]

open access: yesSensors (Basel)
Papanikolaou A   +4 more
europepmc   +1 more source

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