Results 141 to 150 of about 406,792 (258)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Adaptive recognition network for few-shot plant diseases and pests based on homeostatic neuromodulation and meta-plasticity. [PDF]

Front Plant Sci
Zhang X, Zhao Y, Liang K, Zhang Y.
europepmc   +1 more source

Epidemiology and Control of Plant Diseases. [PDF]

Plants (Basel), 2023
Vitale A.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Bacillus strains from Tunisian Sabkhas as promising biocontrol agents for several plant diseases in the Mediterranean. [PDF]

BMC Microbiol
Ben Gharsa H, Bouri M, Schuster C, Rhouma A, Leclerque A.   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Distributed Deep Learning in IoT Sensor Network for the Diagnosis of Plant Diseases. [PDF]

Sensors (Basel)
Papanikolaou A, Tziouvaras A, Floros G, Xenakis A, Bonsignorio F.   +4 more
europepmc   +1 more source

Phloem-Localized Insect-Transmitted Bacteria Associated with Plant Diseases. [PDF]

Microorganisms, 2023
Bertaccini A.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

An ensemble heterogeneous transformer model for an effective diagnosis of multiple plant diseases. [PDF]

Front Plant Sci
Kalpana P, Gera P, Alabdulkreem E, Quasim MT, Baili J, Cho Y, Nam Y.   +6 more
europepmc   +1 more source