Results 101 to 110 of about 1,276,626 (288)

Metabolic profiling and antimicrobial activity of Bistorta amplexicaulis D. don by in-vitro implicated through computational studies

Frontiers in Pharmacology
Ethnopharmacological relevanceBistorta amplexicaulis is an important medicinal plant from the Polygonaceae family. It is been utilized traditionally to cure several ailments. However, its essential bioactivities and antimicrobial mechanisms have remained
Hanan Javid, Umar Yousuf, Roof Ul Qadir, Junaid A. Magray, Bilal A. Wani, Tajamul Islam, Irshad A. Nawchoo, Shabana Gulzar   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Radiating diversification and niche conservatism jointly shape the inverse latitudinal diversity gradient of Potentilla L. (Rosaceae)

BMC Plant Biology
Background The latitudinal diversity gradient (LDG), characterized by an increase in species richness from the poles to the equator, is one of the most pervasive biological patterns. However, inverse LDGs, in which species richness peaks in extratropical
Tiantian Xue, Tao Feng, Yunfen Liang, Xudong Yang, Fei Qin, Jianghong Yu, Steven B. Janssens, Shengxiang Yu   +7 more
doaj   +1 more source

Lotus Seeds: Current Molecular Biology Insights and Future Perspectives as a Prominent Biological Resource

Plants
Lotus (Nelumbo nucifera Gaertn.) is an economically and medicinally significant aquatic plant, with its seeds (lotus seeds) having attracted considerable attention due to their unique developmental traits and abundance of bioactive and nutritional ...
Jia Xin, Ruirui Li, Juan Liu, Xianbao Deng, Dong Yang, Heyun Song, Minghua Zhang, Hui Yang, Runjie He, Yapei Zhang, Heng Sun, Mei Yang   +11 more
doaj   +1 more source

Threatened Limestone Fynbos plant communities of Andrew’s Field and Tsaba-Tsaba Nature Reserve, Western Cape

Bothalia: African Biodiversity & Conservation, 2007
The vegetation of inland plains and hills of the Andrew’s Field and Tsaba-Tsaba Nature Reserve, Bredasdorp District, Western Cape was classified using TWINSPAN and Braun-Blanquet procedures.
M. M. Zietsman, G. J. Bredenkamp
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Genetic Dissection of Root System Architectural Traits in Spring Barley

Frontiers in Plant Science, 2019
Breeding new crop cultivars with efficient root systems carries great potential to enhance resource use efficiency and plant adaptation to unstable climates. Here, we evaluated the natural variation of root system architectural traits in a diverse spring
Zhongtao Jia, Ying Liu, Benjamin D. Gruber, Kerstin Neumann, Benjamin Kilian, Andreas Graner, Nicolaus von Wirén   +6 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Exploring local vegetables cultivated in home gardens of Pa Tio District, Yasothon Province, Thailand: ethnobotanical knowledge, nutritional value, and horticultural potential

Journal of Ethnobiology and Ethnomedicine
Background Local vegetables are essential for food security, nutrition, and cultural practices in rural northeastern Thailand. Despite their importance, comprehensive documentation of their diversity, nutritional contributions, cultural significance, and
Piyaporn Saensouk, Surapon Saensouk, Phiphat Sonthongphithak, Khamfa Chanthavongsa, Tammanoon Jitpromma   +4 more
doaj   +1 more source