Results 101 to 110 of about 2,538,506 (274)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Changes of leaf anatomical profile of cocoa clones seedlings in response to drought.

open access: yesCoffee and Cocoa Research Journal, 2019
Cocoa is a plant that is very sensitive to drought during its growth and development phase, which causes changes up to the anatomical and morphological level.
Fakhrusy Zakariyya   +2 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Effects of melatonin and palmitic acid on the wax content of mango leaf epidermis [PDF]

open access: yesGuoshu xuebao
[Objective] The epidermal wax serves as the primary barrier for plants against external environmental stresses. It plays an important role in preventing water loss from the plant epidermis, inhibiting pathogen invasion and extending the storage period of
WU Jingbo   +8 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate

open access: yesNature Communications, 2018
Plant root hairs elongate in response to low soil phosphate. Here Bhosale et al. show that root hair elongation requires auxin synthesis mediated by TAA1, auxin transport by AUX1 in the lateral root cap and epidermis, and signaling via the auxin ...
Rahul Bhosale   +24 more
doaj   +1 more source

How Cabbage Aphids Brevicoryne brassicae (L.) Make a Choice to Feed on Brassica napus Cultivars

open access: yesInsects, 2019
Plant resistance to aphids might be present in different plant tissues, such as the epidermis, mesophyll and phloem, but not all of them play a key role in determining the feeding preference of aphids.
Zhong-Ping Hao   +3 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Air Pollution Effects on the Leaf Structure of some Fabaceae Species

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2009
Plants growing in the industrial areas and near the major roads absorb the pollutants at their foliar surface. In this paper, histological changes induced by air pollutants (from a cement factory combined with the pollution generated by human activities)
Irina Neta GOSTIN
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

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