Results 81 to 90 of about 1,124 (207)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Changes of leaf anatomical profile of cocoa clones seedlings in response to drought.

open access: yesCoffee and Cocoa Research Journal, 2019
Cocoa is a plant that is very sensitive to drought during its growth and development phase, which causes changes up to the anatomical and morphological level.
Fakhrusy Zakariyya   +2 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Effects of melatonin and palmitic acid on the wax content of mango leaf epidermis [PDF]

open access: yesGuoshu xuebao
[Objective] The epidermal wax serves as the primary barrier for plants against external environmental stresses. It plays an important role in preventing water loss from the plant epidermis, inhibiting pathogen invasion and extending the storage period of
WU Jingbo   +8 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate

open access: yesNature Communications, 2018
Plant root hairs elongate in response to low soil phosphate. Here Bhosale et al. show that root hair elongation requires auxin synthesis mediated by TAA1, auxin transport by AUX1 in the lateral root cap and epidermis, and signaling via the auxin ...
Rahul Bhosale   +24 more
doaj   +1 more source

How Cabbage Aphids Brevicoryne brassicae (L.) Make a Choice to Feed on Brassica napus Cultivars

open access: yesInsects, 2019
Plant resistance to aphids might be present in different plant tissues, such as the epidermis, mesophyll and phloem, but not all of them play a key role in determining the feeding preference of aphids.
Zhong-Ping Hao   +3 more
doaj   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

open access: yesArthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge   +6 more
wiley   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

open access: yesAdvanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim   +6 more
wiley   +1 more source

Air Pollution Effects on the Leaf Structure of some Fabaceae Species

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2009
Plants growing in the industrial areas and near the major roads absorb the pollutants at their foliar surface. In this paper, histological changes induced by air pollutants (from a cement factory combined with the pollution generated by human activities)
Irina Neta GOSTIN
doaj   +1 more source

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