Results 101 to 110 of about 609,939 (306)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

DCAF13-mediated K63-linked ubiquitination of RNA polymerase I promotes uncontrolled proliferation in Breast Cancer

Nature Communications
Hyperactivation of ribosome biogenesis (RiBi) drives cancer progression, yet the role of RiBi-associated proteins (RiBPs) in breast cancer (BC) is underexplored.
Zhi-Zhi Yang, Bing Yang, Haiyan Yan, Xingyu Ma, Bin Tian, Bingqi Zheng, Yong-Xian Chen, Yi-Ming Dong, Jinsi Deng, Ziling Zhan, Yanmei Shi, Jing Yuan Zhang, Daning Lu, Jie-Hua He, Yin Zhang, KaiShun Hu, Shuang Zhu, Keda Zhou, Yu-Chan Zhang, Yiqing Zheng, Dong Yin, Jian-You Liao   +21 more
doaj   +1 more source

LncRNAs: genetic and epigenetic effects in plants

Biotechnology & Biotechnological Equipment, 2019
Long non-coding RNAs (lncRNAs) transcribed from the eukaryotic genome play important roles in essential biological processes, transcriptional and post-transcriptional gene regulation.
Elif Karlik, Sule Ari, Nermin Gozukirmizi   +2 more
doaj   +1 more source

The HY5-PIF regulatory module coordinates light and temperature control of photosynthetic gene transcription [PDF]

, 2014
The ability to interpret daily and seasonal alterations in light and temperature signals is essential for plant survival. This is particularly important during seedling establishment when the phytochrome photoreceptors activate photosynthetic pigment ...
A Alboresi, A Ben-Shem, A Fukushima, A Kunihiro, A Pokhilko, A Pokhilko, B Al-Sady, B Berckmans, C Andronis, C Kami, CS Hardtke, D Alabadi, D Chen, DC Rockholm, E Huq, E Lopez-Juez, E Park, G Toledo-Ortiz, Gabriela Toledo-Ortiz, Gavin Steel, H Shen, H Shen, H Zhang, Henrik Johansson, J Foreman, J Lee, J Li, J Moon, J Shin, J Shin, J Shin, J Soy, J Sun, JA Stavang, JC del Pozo, JF Martinez-Garcia, JM Tepperman, Jordi Bou-Torrent, K Kobayashi, K Nozue, KA Franklin, KA Franklin, KA Franklin, Karen J. Halliday, Kelly Stewart, Keun Pyo Lee, KK Niyogi, Li-Jia Qu, M de Lucas, M Havaux, MA Koini, Manuel Rodríguez-Concepción, MC Proveniers, MF Covington, MH Walter, MT Osterlund, N Mochizuki, N Mochizuki, OS Lau, P Hornitschek, P Hornitschek, P Leivar, P Leivar, P Leivar, P Leivar, PG Stephenson, PH Quail, PH Quail, R Catala, R Henriques, R Welsch, S Chattopadhyay, S Ito, S Lorrain, S Makino, S Reinbothe, S Toh, SV Kumar, T Legnaioli, T Oyama, T Yamashino, T Yamashino, W Huang, Y Niwa, Y Nomoto, Y Nomoto, Y Zhang, Y Zhang, Y Zhang   +88 more
core   +5 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The Phaseolus vulgaris PvTRX1h gene regulates plant hormone biosynthesis in embryogenic callus from common bean

Frontiers in Plant Science, 2015
Common bean is the most important grain legume in the human diet. Bean improvement efforts have been focused on classical breeding techniques because bean is recalcitrant to both somatic embryogenesis and in vitro regeneration.
Aarón eBarraza, José Luis eCabrera-Ponce, Roberto eGamboa-Becerra, Francisco eLuna-Martínez, Robert eWinkler, Raúl eAlvarez-Venegas   +5 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Role of MicroRNAs in Genome Response to Plant–Lepidoptera Interaction

Plants, 2019
RNA interference is a known phenomenon of plant immune responses, involving the regulation of gene expression. The key components triggering the silencing of targeted sequences are double-stranded RNA molecules.
Katarína Ražná, Ľudovít Cagáň
doaj   +1 more source

Mechanism of Fruit Ripening - Chapter 16 [PDF]

, 2010
The fruit ripening process has been viewed over the last decades as being successively of physiological, biochemical, and molecular nature. Fruit ripening is accompanied by a number of biochemical events, including changes in color, sugar, acidity ...
Bouzayen, Mondher, Latché, Alain, Nath, Pavendra, Pech, Jean-Claude   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source