Results 261 to 270 of about 7,959,234 (301)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

The MdSLR1b-MdKNOX15-MdGA20ox2/MdGA2ox7 module regulates dwarfing by mediating the gibberellin pathway in apple. [PDF]

Plant J
Yan R, Zeng X, Wang Y, Wang N, Yang Y, Liang B, Zhang X, Qi G, Jia P.   +8 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Role of cell wall-associated kinases in plant development and defense responses. [PDF]

Mol Biol Rep
Asemoloye MD, Olowe OM.
europepmc   +1 more source

Functional Characterization and Transcriptional Regulation of Olive Tocopherol Methyltransferase Responsible for the Vitamin E Content of Virgin Olive Oil. [PDF]

J Agric Food Chem
Muñoz-Ocaña C, Narváez I, Sicardo MD, Hernández ML, Moreda W, Martínez-Rivas JM.   +5 more
europepmc   +1 more source

Loss of AtPLC1 Impairs Salt-Alkali Tolerance via Disruption of Stomatal Regulation and Redox Homeostasis in <i>Arabidopsis thaliana</i>. [PDF]

Plants (Basel)
Li X, Wang Y, Si L, Sun D, Wang N, Liu W, Dong Y, Li X, Wang F.   +8 more
europepmc   +1 more source

Soybean α-Amylase Gene Family: Structure and Expression in Response to Abiotic Stresses. [PDF]

Int J Mol Sci
Filyushin MA, Shchennikova AV, Shilova KO, Kochieva EZ, Divashuk MG.   +4 more
europepmc   +1 more source

CRISPR-Cas technologies for precision genome editing in plants: advances, applications, and future perspectives. [PDF]

Front Plant Sci
Riaz Ahmed S, Khan J, Ijaz I, Ali Z, Rasul I, Aslam M, Ud-Din N, Liu Y, Tariq MS, Skalicky M, Tan DKY.   +10 more
europepmc   +1 more source

Genome-Wide Identification of the R2R3-MYB Gene Family in <i>Solanum americanum</i> and Functional Analysis of Its Role in Fruit Coloration. [PDF]

Biology (Basel)
Yang Y, Gong Z, Wang Y, Li H, Li J, Cai Q, Luo Z, Sun Z, Li L.   +8 more
europepmc   +1 more source

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Evidence of Cross-Kingdom Gene Regulation by Plant MicroRNAs and Possible Reasons for Inconsistencies

Journal of Agricultural and Food Chemistry
The debate on whether cross-kingdom gene regulation by orally acquired plant miRNAs is possible has been ongoing for nearly 10 years without a conclusive answer.
Diyao Wu, Xu Tie-Long
exaly   +2 more sources