Results 151 to 160 of about 532,858 (293)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Reliable genomic strategies for species classification of plant genetic resources. [PDF]

open access: yesBMC Bioinformatics, 2021
van Bemmelen van der Plaat A   +2 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

CGIAR Policy on Plant Genetic Resources [PDF]

open access: yes, 1989
A published version in English, French and Spanish of the statement of policy on plant genetic resources approved by the CGIAR at its annual meeting in October-November 1988.
CGIAR
core  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Plant genetic resources: foundations for a food-secure and climate-resilient future in the Caribbean [PDF]

open access: yes, 2014
Across the Caribbean, climate change will bring about not only challenges but also a wide array of opportunities, which lend greater significance to the region’s wealth of plant genetic resources. Realizing the potential of those resources to help ensure
Castañeda-Álvarez, Nora P.   +8 more
core  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Participatory Plant Breeding for Organic Farming in France, the cauliflower experience at the PAIS [PDF]

open access: yes, 2005
The availability of organic seeds is a great problem for organic farmers. The private sector of plant breeding meets difficulties to answer to the organic farming (OF) demand, characterized by small quantities and a great diversity of criteria and by ...
Chable, Dr Véronique   +1 more
core  

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