Results 131 to 140 of about 209,914 (307)

In silico development and validation of EST derived new SSR markers for drought tolerance in Cicer arietinum L.

open access: yes, 2014
Microsatellites have become a marker of choice in plant genetics and breeding research due to their unilocus, multiallelic and highly reproducible nature. In present study EST sequences isolated from chickpea root under water stress were assessed for the
Bhardwaj, Juhi   +7 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Italian contribution to plant genetics and breeding - Hazelnut

open access: yes, 1998
The Italian contribution to hazelnut genetics and breeding in the last decades is ...
BIGNAMI, Cristina, TOMBESI A, ME G
core  

Current Advancement and Future Prospects in Simplified Transformation-Based Plant Genome Editing

open access: yes
Recent years have witnessed remarkable progress in plant biology, driven largely by the rapid evolution of CRISPR/Cas-based genome editing (GE) technologies.
Zhaolong Deng   +3 more
core   +1 more source

The history of plant genetics studies in plant breeding and genetics institute for 100 years

open access: yesФактори експериментальної еволюції організмів, 2013
Aims. New generation of scientists is almost not acquainted with the “lysenkoism” period in the home biological science. Here is the attempt to represent some data with the example of PBGI. Methods.
A. F. Stelmakh, V. I. Fayt
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

USDA-CSREES Review: Self-assessment Study and Appendix

open access: yes, 2008
Self-Assessment Study, 110 pages; Appendix, 86 pagesSince our last review [in 1992], our areas of research, education and outreach have shifted from traditional discipline-based programs to a more holistic, interdisciplinary approach to solving the ...
Department of Agronomy and Plant Genetics
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

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