Results 111 to 120 of about 3,038,545 (246)

6. Innovations in plant breeding: New concepts in whole-plant genetics

open access: yesCalifornia Agriculture, 1982
Wheat-barley hybrids/Jan, Qualset, Dvorak; Induced chromosome pairing/Irvine, McGuire; Hybridization in Strawberries/Bringhurst, Voth; Pollen selection/R. A.
T Orton
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Special Issue “Molecular Genetics and Plant Breeding 3.0 and 4.0”

open access: yes
Molecular genetics aims to understand the genetic principles and functions of genes at the molecular level, while plant breeding aims to apply this information to improve plant traits and develop new crop varieties with desired characteristics [...
Du, Hai, Hai Du
core   +1 more source

Genome Wide Identification and Characterization of BrE2F Family Gene of Brassica rapa

open access: yesInternational Journal of Genomics
The E2F family gene is one of the most important G1–S checkpoint regulatory transcription factors to monitor and regulate the accurate DNA replication and progression of the cell cycle in eukaryotes.
Naima Sultana   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The history of plant genetics studies in plant breeding and genetics institute for 100 years

open access: yesФактори експериментальної еволюції організмів, 2013
Aims. New generation of scientists is almost not acquainted with the “lysenkoism” period in the home biological science. Here is the attempt to represent some data with the example of PBGI. Methods.
A. F. Stelmakh, V. I. Fayt
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Microdeletions and molecular genetics

open access: yes, 2004
Educational Items on Microdeletions and molecular ...
Fryns, JP, A Vogels, JP Fryns, Vogels, A
core   +1 more source

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