Results 101 to 110 of about 209,914 (307)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Plant Short-Chain Dehydrogenase (SDR) superfamily:genome-wide inventory and diversification patterns [PDF]

, 2012
Background Short-chain dehydrogenases/reductases (SDRs) form one of the largest and oldest NAD(P)(H) dependent oxidoreductase families. Despite a conserved 'Rossmann-fold' structure, members of the SDR superfamily exhibit low sequence similarities, which
Moummou, Hanane, Persson, B, van der Rest, Benoit,, Libert Brice Tonfack, Tonfack, LB, Tonfack, Libert Brice, Kallberg, Yvonne, Persson, Bengt, Bengt Persson, Kallberg, Y,, Benoît van der Rest, Moummou, Hanane,, Yvonne Kallberg, Brice Tonfack, Libert, Persson, Bengt,, Hanane Moummou, Van der Rest, Benoît, Kallberg, Yvonne,, Brice Tonfack, Libert,, van, der Rest B, Moummou, H   +20 more
core   +1 more source

Ethnographie de la mise à l’agenda scientifique de l’agroécologie dans un laboratoire de génétique végétale

VertigO
Since the late 2000s, the term “agroecology” has been gaining ground in agronomic research organizations (INRAE, CIRAD), in calls for research projects and in scientific publications. Plant genetics is no exception to this trend, but the appropriation of
Margot Buzaré
doaj   +1 more source

Genome-wide identification of aquaporin encoding genes in Brassica oleracea and their phylogenetic sequence comparison to Brassica crops and Arabidopsis

Frontiers in Plant Science, 2015
Aquaporins (AQPs) are essential channel proteins that regulate plant water homeostasis and the uptake and distribution of uncharged solutes such as metalloids, urea, ammonia and carbon dioxide.
Till Arvid Diehn, Benjamin ePommerrenig, Nadine eBernhardt, Anja eHartmann, Gerd Patrick Bienert   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Balancing selection and its effects on sequences in nearby genome regions. [PDF]

, 2006
Our understanding of balancing selection is currently becoming greatly clarified by new sequence data being gathered from genes in which polymorphisms are known to be maintained by selection.
Deborah Charlesworth, Charlesworth Deborah, Charlesworth, Deborah   +2 more
core   +1 more source

Optimizing experimental procedures for quantitative evaluation of crop plant performance in high throughput phenotyping systems

Frontiers in Plant Science, 2015
Detailed and standardized protocols for plant cultivation in environmentally controlled conditions are an essential prerequisite to conduct reproducible experiments with precisely defined treatments.
Astrid eJunker, Moses Mahugu Muraya, Kathleen eWeigelt-Fischer, Fernando eArana-Ceballos, Christian eKlukas, Albrecht E Melchinger, Rhonda C Meyer, David eRiewe, Thomas eAltmann   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Molecular Mapping in Barley: Shifting from the Structural to the Functional Level

Czech Journal of Genetics and Plant Breeding, 2005
As a resource for structural and functional barley genome analysis, more than 140 000 ESTs (expressed sequence tags) were generated from 22 cDNA libraries that yielded 25 224 tentative unigenes. About 50% of them belong to gene families.
A Graner, T Thiel, H Zhang, E Potokina, M Prasad, D Perovic, R Kota, R K Varshney, U Scholz, I Grosse, N Stein   +10 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source