Results 91 to 100 of about 3,038,545 (246)

Genome-wide identification of aquaporin encoding genes in Brassica oleracea and their phylogenetic sequence comparison to Brassica crops and Arabidopsis

Frontiers in Plant Science, 2015
Aquaporins (AQPs) are essential channel proteins that regulate plant water homeostasis and the uptake and distribution of uncharged solutes such as metalloids, urea, ammonia and carbon dioxide.
Till Arvid Diehn, Benjamin ePommerrenig, Nadine eBernhardt, Anja eHartmann, Gerd Patrick Bienert   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Plant chemical genetics : from phenotype-based screens to synthetic biology [PDF]

, 2017
The treatment of a biological system with small molecules to specifically perturb cellular functions is commonly referred to as chemical biology. Small molecules are used commercially as drugs, herbicides, and fungicides in different systems, but in ...
Russinova, Eugenia, Russinova, EugeniaWE098010020905100000-0002-0569-1977F8175D1C-F0ED-11E1-A9DE-61C894A0A6B4, Dejonghe, Wim, Wim Dejonghe, Dejonghe, WimUGent0020032784538020009184059745628212910CE4E1CE-F0EE-11E1-A9DE-61C894A0A6B4, Eugenia Russinova   +5 more
core   +1 more source

Molecular Mapping in Barley: Shifting from the Structural to the Functional Level

Czech Journal of Genetics and Plant Breeding, 2005
As a resource for structural and functional barley genome analysis, more than 140 000 ESTs (expressed sequence tags) were generated from 22 cDNA libraries that yielded 25 224 tentative unigenes. About 50% of them belong to gene families.
A Graner, T Thiel, H Zhang, E Potokina, M Prasad, D Perovic, R Kota, R K Varshney, U Scholz, I Grosse, N Stein   +10 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Toward a Molecular Understanding of Plant Hormone Actions [PDF]

, 2016
Plants rely on a diverse set of small-molecule hormones to regulate every aspect of their biological processes including development, growth, and adaptation. Since the discovery of the first plant hormone, auxin, hormones have always been at the frontier
Matsuoka, M., Lee, Y., Li, Jiayang, Matsuoka, Makoto, Li, J.Y., Schroeder, J., Lee, Youngsook, Leung, Jeffrey, Zhao, Y.D., Harter, Klaus, Qu, L.J., Li, C.Y., Li, Chuanyou, Offringa, Remko, Qu, Lijia, Martinoia, Enrico, Zhao, Yunde, Chong, K., Offringa, R., Leung, J., Schroeder, Julian, Harter, K., Chong, Kang, Martinoia, E.   +23 more
core   +1 more source

Shaping science with the past : textbooks, history, and the disciplining of genetics [PDF]

, 2008
Science is generally not thought of as being deeply historiographical. Although it is clear that scientists frequently write about history in their work — that, for example, they identify the significance of an advance by situating it historically, or ...
Skopek, Jeffrey M, Jeffrey Skopek
core   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source