Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Corrigendum - Butterfly host plant Monograph
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doaj +1 more source
On connections between lixine weevils and different plant organs (Coleoptera, Curculionidae, Lixinae) [PDF]
Наbitat and feeding of the weevils from subfamily Lixinae are considered. As to larvae specialization three groups of these beetles are pointed: rhizophagous, caulophagous and anthocarpophagous.
S.V. Volovnik
doaj +1 more source
\u3ci\u3eCoreopsis Tinctoria\u3c/i\u3e: An Unrecorded Host Plant of Adult \u3ci\u3eCalligrapha Callfornica Coreopsivora\u3c/i\u3e (Coleoptera: Chrysomelidae) [PDF]
Adults of Calligrapha californica coreopsivora are recorded feeding upon cultivated Coreopsis tinctoria in southwestern Virginia.
Williams, Charles E
core +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
A molecular tug-of-war: Global plant proteome changes during viral infection
Plant pathogenic viruses cause a number of economically important diseases in food, fuel, and fiber crops worldwide. As obligate parasites with highly reduced genomes, viruses rely heavily on their hosts for replication, assembly, intra- and ...
Mariko M. Alexander, Michelle Cilia
doaj +1 more source
Various chemical strategies to deceive ants in three Arhopala species (lepidoptera: Lycaenidae) exploiting Macaranga myrmecophytes. [PDF]
Macaranga myrmecophytes (ant-plants) are generally well protected from herbivore attacks by their symbiotic ants (plant-ants). However, larvae of Arhopala (Lepidoptera: Lycaenidae) species survive and develop on specific Macaranga ant-plant species ...
Yoko Inui +4 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source

