Results 111 to 120 of about 131,305 (342)

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Harnessing microbiome-plant synergies: microbiome-interactive traits enhance plant growth and support sustainable agriculture

npj Sustainable Agriculture
The interaction between plant cultivars and the soil microbiome is essential for agricultural productivity. We hypothesise that cultivars with a strong microbiome interactive trait (MIT) can reach high performance with reduced dependence on chemical inputs.
Zhao, Tianci, Jia, Xiu, Liu, Xipeng, Nepal, Jyotsna, Guyoneaud, Rémy, Treder, Krzysztof, Pawłowska, Anna, Michałowska, Dorota, Berg, Gabriele, Stocker, Franz, Cernava, Tomislav, Elzenga, J. Theo M., Attard, Eléonore, Salles, Joana Falcão   +13 more
openaire   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Ecology and Evolution of Plant Microbiomes

Annual Review of Microbiology, 2019
Microorganisms colonizing plant surfaces and internal tissues provide a number of life-support functions for their host. Despite increasing recognition of the vast functional capabilities of the plant microbiome, our understanding of the ecology and evolution of the taxonomically hyperdiverse microbial communities is limited.
Cordovez, V., Dini-Andreote, F., Carrión, V.J., Raaijmakers, J.M.   +3 more
openaire   +3 more sources

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Nav1.8-expressing neurons control daily oscillations of food intake, body weight and gut microbiota in mice

Communications Biology
Recent evidence suggests a role of sensory neurons expressing the sodium channel Nav1.8 on the energy homeostasis control. Using a murine diphtheria toxin ablation strategy and ad libitum and time-restricted feeding regimens of control or high-fat high ...
Clara Bullich-Vilarrubias, Marina Romaní-Pérez, Inmaculada López-Almela, Teresa Rubio, Carlos J. García, Francisco A. Tomás-Barberán, Yolanda Sanz   +6 more
doaj   +1 more source

Going back to the Roots: Impact of the microbiome on plant health and growth [PDF]

, 2018
Conferencia científicaPlant roots are colonized by an astounding number of microorganisms that can reach cell densities much greater than the number of plant cells.
Carrión, Víctor J.
core  

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Adaptations in gut Bacteroidales facilitate stable co-existence with their lytic bacteriophages

Gut Microbes
Bacteriophages (phages) and bacteria within the gut microbiome persist in long-term stable coexistence. These interactions are driven by eco-evolutionary dynamics, where bacteria employ a variety of mechanisms to evade phage infection, while phages rely ...
Adrián Cortés-Martín, Colin Buttimer, Jessie L. Maier, Ciara A. Tobin, Lorraine A. Draper, R. Paul Ross, Manuel Kleiner, Colin Hill, Andrey N. Shkoporov   +8 more
doaj   +1 more source

The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report. [PDF]

, 2016
The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium is a novel, interdisciplinary initiative comprised of experts across many fields, including genomics, data analysis, engineering, public health, and ...
MetaSUB International Consortium
core   +1 more source