Results 101 to 110 of about 363,951 (284)

Some Causes Underlying Cellular Differentiation [PDF]

open access: yes, 1958
Author Institution: Department of Botany and Plant Pathology, Ohio State University, Columbus ...
Popham, Richard A.
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Thiamine is a vitamin for plant-pathogenic powdery mildew fungi

open access: yesiScience
Summary: Thiamine (vitamin B1) is an essential micronutrient in all forms of life that serves as a cofactor for several enzymes in primary metabolism.
Björn Sabelleck   +7 more
doaj   +1 more source

Digital plant pathology: a foundation and guide to modern agriculture. [PDF]

open access: yesJ Plant Dis Prot (2006), 2022
Kuska MT   +5 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Plant Pathology and Public Health

open access: yesEmerging Infectious Diseases, 1999
Karen-Beth G. Scholthof
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Production and physicochemical characterization of exopolysaccharides from the salt-tolerant actinobacterial strain Zhihengliuella halotolerans DT-Z1

open access: yesiScience
Summary: Extremophiles often produce exopolysaccharides (EPSs) as a strategy in harsh environments, thus attracting significant interest for their properties and applications.
Chengyang Wang   +5 more
doaj   +1 more source

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