Results 1 to 10 of about 639,733 (219)

Attachment of Ferredoxin: NADP+ Oxidoreductase to Phycobilisomes Is Required for Photoheterotrophic Growth of the Cyanobacterium Synechococcus sp. PCC 7002

open access: yesMicroorganisms, 2022
Two types of cyanobacterial phycobilisomes (PBS) are present: the hemidiscoidal PBS (CpcG-PBS) and the membrane-bound PBS (CpcL-PBS). Both types of PBS have ferredoxin:NADP+ oxidoreductase (FNR) attached to the termini of their rods through a CpcD domain.
Xiying Li   +8 more
doaj   +1 more source

m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome

open access: yesNature Communications, 2021
m6Am is a dynamic and reversible RNA modification found on the mRNA cap. Here the authors report m6Am-seq to directly distinguish m6Am from m6A and identify functional methylation sites.
Hanxiao Sun   +6 more
doaj   +1 more source

Arabidopsis TCP4 transcription factor inhibits high temperature-induced homeotic conversion of ovules

open access: yesNature Communications, 2023
Abnormal high temperature (HT) caused by global warming threatens plant survival and food security, but the effects of HT on plant organ identity are elusive.
Jingqiu Lan   +6 more
doaj   +1 more source

RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity

open access: yesNature Communications, 2022
The 53BP1-RIF1 pathway is important for DNA repair. Here, the authors identified the histone chaperone ASF1, which functions as a suppressor of DNA end resection through changing high-order chromatin structure, as a partner of RIF1.
Sumin Feng   +12 more
doaj   +1 more source

Determinants of genome-wide distribution and evolution of uORFs in eukaryotes

open access: yesNature Communications, 2021
Upstream open reading frames (uORFs) have widespread regulatory functions in eukaryotes, their genomic distribution and evolution is understudied. Here, the authors characterise ~17 million putative uORFs across 478 eukaryotic species, showing how ...
Hong Zhang   +5 more
doaj   +1 more source

Author Correction: Determinants of genome-wide distribution and evolution of uORFs in eukaryotes

open access: yesNature Communications, 2021
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22435 ...
Hong Zhang   +5 more
doaj   +1 more source

Tissue-specific 5-hydroxymethylcytosine landscape of the human genome

open access: yesNature Communications, 2021
Charting the landscape of 5hmC in human tissues is fundamental to understanding its regulatory functions. Here, we systematically profiled the whole-genome 5hmC landscape at single-base resolution for 19 types of human tissues and found 5hmC shows tissue-
Bo He   +11 more
doaj   +1 more source

Manipulating the Bacterial Cell Cycle and Cell Size by Titrating the Expression of Ribonucleotide Reductase

open access: yesmBio, 2017
Understanding how bacteria coordinate growth with cell cycle events to maintain cell size homeostasis remains a grand challenge in biology. The period of chromosome replication (C period) is a key stage in the bacterial cell cycle. However, the mechanism
Manlu Zhu   +6 more
doaj   +1 more source

An OB-fold complex controls the repair pathways for DNA double-strand breaks

open access: yesNature Communications, 2018
How repair pathway selection occurs is still a matter of debate and many factors have been associated to this function. Here the authors provide insight into the role of FAM35A and C20ORF196, two REV7-interacting proteins, which are recruited at double ...
Shengxian Gao   +10 more
doaj   +1 more source

Deciphering TAL effectors for 5-methylcytosine and 5-hydroxymethylcytosine recognition

open access: yesNature Communications, 2017
Transcription activator-like effector proteins recognise specific DNA sequences via tandem repeats. Here the authors demonstrate TALEs can recognise the methylated bases 5mC and 5hmC, enabling them to detect epigenetic modifications.
Yuan Zhang   +7 more
doaj   +1 more source

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