Results 151 to 160 of about 4,454,677 (302)

Exploring the biodiversity of plant proteins for sustainable foods: Composition and emulsifying properties of the proteins recovered by aqueous extraction from camelina (Camelina sativa L.) seeds

open access: yesCurrent Research in Food Science
The food transition towards an increased consumption of plant proteins aimed at limiting environmental impacts requires a diversification of plant protein sources.
Christelle Lopez   +5 more
doaj   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

open access: yesAdvanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha   +5 more
wiley   +1 more source

Dietary intake of total, animal, and plant proteins and risk of chronic kidney disease: systematic review and dose-response meta-analysis of prospective cohort studies

open access: yesBMC Nutrition
Objective Kidney health and dietary protein consumption are incompatible. This study aimed to examine the association between different types of proteins (total, animal, and plant) and chronic kidney disease (CKD).
Sepide Talebi   +4 more
doaj   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

open access: yesAdvanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu   +13 more
wiley   +1 more source

Cloning and characterisation of LEA1-EM genes in the resurrection plant, Xerophyta humilis [PDF]

open access: yes, 2008
Includes abstract.Includes bibliographical references (leaves 75-86).The presence and expressIon patterns of orthologues of LEA group 1 genes has been characterised in the resurrection plant, Xerophyta humilis.
Ngubane, Nqobile A C
core   +1 more source

Charting Endocrine Progenitors Across Species and Organs

open access: yesAdvanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing   +21 more
wiley   +1 more source

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun   +7 more
wiley   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu   +13 more
wiley   +1 more source

Dietary plant-based protein improves the growth performance and health status of Colossoma macropomum

open access: yes
Abstract This study evaluated the effect of isonitrogenous and isocaloric diets based on animal protein (AP) and plant protein (PP), on growth performance, feed cost and body composition of tambaqui in the phases of on-growing and grow-out.
Paulo Adelino Medeiros   +5 more
openaire   +1 more source

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