Results 81 to 90 of about 4,394,496 (234)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Genotype and Production Year Effects on urdbean [Vigna mungo (L.) Hepper] Performance in Virginia

HortScience
Urdbean [Vigna mungo (L.) Hepper], a legume crop that is grown in many parts of the world as a nutritious food source, is a potential alternative crop for the southern United States as a food and plant protein crop.
Harbans L. Bhardwaj, Satya S. Narina, Ramesh Dhakal   +2 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Analysing Novel Structures of Protein Complexes Requiring the Central Plant Immune Regulator EDS1 [PDF]

, 2013
Plants as sessile organisms are constantly attacked by pathogens and have evolved a complex immune system to cope with this challenge. The first inducible layer of plant immunity recognises pathogens outside each plant cell and activates a resistance ...
Wagner, Stephan
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The Cyst Nematode SPRYSEC Protein RBP-1 Elicits Gpa2- and RanGAP2-Dependent Plant Cell Death [PDF]

, 2009
Plant NB-LRR proteins confer robust protection against microbes and metazoan parasites by recognizing pathogen-derived avirulence (Avr) proteins that are delivered to the host cytoplasm.
Moffett, Peter, Alexandra Blanchard, Goverse Aska, Smant, G., Sacco, Melanie Ann, Koropacka, Kamila, Smant Geert, Peter Moffett, Grenier, E., Jaubert, Marianne J., Grenier, Eric, Goverse, A., Blanchard, A., Kamila Koropacka, Melanie Ann Sacco, Aska Goverse, Goverse, Aska, Moffett, P., Smant, Geert, Geert Smant, Koropacka, K.B., Blanchard, Alexandra, Moffett Peter, Jaubert Marianne J., Koropacka Kamila, Eric Grenier, Sacco, M.A., Sacco Melanie Ann, Marianne J Jaubert, Jaubert, M.J., Grenier Eric, Blanchard Alexandra   +31 more
core   +1 more source

IMPROVEMENT OF MEAT PATE PRODUCTS THROUGH THE USE OF PLANT PROTEINS

Шәкәрім университетінің хабаршысы: Техника ғылымдар
This article discusses the importance of the application of plant proteins in meat products, with a particular focus on meat pâté production. The nutritional value of plant proteins and their role in the composition of meat products are analyzed.
G. B. Token, A. M. Taeva, Zh. Zh. Smailova, Z. T. Sarsenbaeva   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Wet-Spinning Technology for Plant-Based Meat Alternative: Influence of Protein Composition on Physicochemical and Textural Properties

Foods
The development of a fibrous-structured meat alternative that can perfectly mimic the tribology of the meat is considered to be extremely challenging. In this study, a bottom-up technique, wet spinning, was used to produce a fiber-like structure similar ...
Swati Kumari, So-Hee Kim, Chan-Jin Kim, Young-Hwa Hwang, Seon-Tea Joo   +4 more
doaj   +1 more source