Results 71 to 80 of about 3,057 (180)

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

The Embryonic Development of the Cotylean Polyclad Phrikoceros jannetae

Acta Zoologica, EarlyView.
ABSTRACT Polyclads exhibit distinct developmental modes ranging from direct to indirect development, with several transitional stages also recognised. The existence of an indirect developmental mode in polyclads with a planktonic life history stage in the form of a free‐swimming larva is unique among all free‐living flatworms and makes polyclads a ...
Mehrez Gammoudi, Bernhard Egger, Isabel L. Dittmann, Verónica N. Bulnes, Pavel Tomancak, Abdel Halim Harrath, Johannes Girstmair   +6 more
wiley   +1 more source

Extracellular fluid viscosity influences the mechanics and migration of MDA‐MB‐231 cells in a macromolecule‐dependent manner

The FEBS Journal, EarlyView.
Macromolecule‐dependent increases in extracellular fluid viscosity alter cell phenotype. These distinct macromolecules create different extracellular environments that modulate cell morphology and mechanoprotein expression, migration and invasion capacity, and cellular mechanical properties.
Ian M. Smith, Nikka Givpoor, Chenchen Handler, Ariel Abraham, Shohini Banerjee, Giuliano Scarcelli, Kimberly M. Stroka   +6 more
wiley   +1 more source

REGENERATION OF Agave marmorata Roezl PLANTS, BY SOMATIC EMBRIOGENESIS

Tropical and Subtropical Agroecosystems, 2020
Background. Agave marmorata Roezl is a monocot plant of the Asparagaceae family, which is mainly used in the elaboration of the alcoholic drink called mezcal. This species is propagated by seeds or stolons (hijuelos), but its reproduction is slow because
Carlos Alvarez-Aragón, Amaury-M. Arzate-Fernandez, Sandra-Yarenssy Martínez-Martínez, Irene Martínez-Velasco   +3 more
doaj  

Taxonomic inflation in fish systematics: A critical review with illustrative evidence assessment and integrative case study of the Salmo trutta Complex

Journal of Fish Biology, EarlyView.
Abstract Fish species are being described at an accelerating rate, but a substantial fraction of recent descriptions rests on evidentiary standards too weak to distinguish genuine species‐level discontinuities from intraspecific variation, local adaptation and the artefacts of single‐marker analyses, a pattern of taxonomic inflation with documented ...
Ilhan Altinok
wiley   +1 more source

20th Anniversary of human‐induced pluripotent stem cells and the role of microscopy

Journal of Microscopy, EarlyView.
Abstract It has been 20 years since the pioneering work of Shinya Yamanaka and Kazutoshi Takahashi at Kyoto University led to the first successful generation of induced pluripotent stem cells (iPSCs) from mouse embryonic and adult fibroblast cells. iPSCs have the capacity to differentiate into any type of cell in the human body, and as such, they have ...
Philomena Hallford, Colette J. Mustard, Nicole Brace, Antonia L. Pritchard   +3 more
wiley   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Phytochemical Evaluation and Plant Regeneration Through Somatic Embryogenesis of Ferulago angulata subsp. Carduchorum (Boiss. and Hausskn), an Endangered Medicinal Plant

Journal of Medicinal Plants, 2017
Background: Ferulago angulata is an important medicinal plant and endemic to Iran which is an endangered Plant. Objective: The aim of this study was to achieve an efficient method for propagation of this plant and evaluation of essential oil content and ...
HA Naghdi Badi, Sh Salek Hashemi, AA Nasrollahnezhad Qomi, Saeed Navabpour, A Qaderi   +4 more
doaj  

Electrochemical impedance spectroscopy as a micropropagation monitoring tool for plants: A case study of tamarillo Solanum betaceum callus

iScience
Summary: Tamarillo is an economically important species that has been extensively studied in terms of in vitro morphogenesis and micropropagation techniques, including somatic embryogenesis.
André Caeiro, Jorge Canhoto, Paulo R.F. Rocha   +2 more
doaj   +1 more source

A Robust Framework for Maize Elite Line Genome Editing Through Enhanced HI‐Edit via LbCas12a Activity Optimization

Plant Biotechnology Journal, EarlyView.
ABSTRACT Haploid induction coupled with genome editing (HI‐Edit) enables direct modification of commercial crop varieties, bypassing the need for trait introgression or direct transformation of elite lines with CRISPR machinery. However, its widespread application has been constrained by low haploid editing rates (HER), the proportion of haploids ...
Dawei Liang, Huanhuan Guo, Juan Wei, Fugui Zhu, Yuguo Zhang, Julie Green, Yun Ji, Huaibing Jin, Xiujuan Zhang, Huaping Gui, Hongmei Dan, Yubo Liu, Yu Zhang, Han Wang, Yutong Jiang, Lizhao Geng, Jian Lv, Wen Cai, Weibin Song, Timothy Kelliher, Xi Chen, Rachel Egger   +21 more
wiley   +1 more source