Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu +3 more
wiley +1 more source
Auxin-induced AsARF16 complex orchestrates lncRNA125175-mediated ceRNA networks to regulate garlic somatic embryogenesis. [PDF]
Bai Y +11 more
europepmc +1 more source
Effects of fluorescence‐activated sperm sorting on IVF outcomes and motility subpopulations. Distinct boar ejaculates were either used directly for in vitro fertilization (IVF; control, unsorted) or processed by fluorescence‐activated cell sorting to generate a sorted sperm population.
Isabel Rodriguez +9 more
wiley +1 more source
Genome-Wide Analysis of <i>PP2C</i> Gene Family and Identification of <i>DlPP2C1</i> as an ABA-Responsive Candidate Regulator During Early Somatic Embryogenesis in Longan (<i>Dimocarpus longan</i> Lour.). [PDF]
Awais M +10 more
europepmc +1 more source
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek +3 more
wiley +1 more source
FANS uncovers WOX2-associated early regulators of auxin-induced somatic embryogenesis in Arabidopsis. [PDF]
Wójcik AM +5 more
europepmc +1 more source
Pitfalls and missing links in current understanding of 4D genomes
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley +1 more source
Direct somatic embryogenesis, genetic fidelity assessment and GC-MS analysis of regenerated Crinum asiaticum L. Plants. [PDF]
Bansal Y +5 more
europepmc +1 more source
Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito +2 more
wiley +1 more source
Macaw Palm Propagation Strategies: Advances, Gaps, and Future Directions for a Promising Oleaginous Crop-A Review. [PDF]
Cavalcanti VP +8 more
europepmc +1 more source

