Results 111 to 120 of about 6,007,853 (334)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

PLASTIC COVERING, PLANTING DENSITY, AND PRUNNING IN THE PRODUCTION OF CAPE GOOSEBERRY (Physalis peruviana L.) IN SUBTROPICAL REGION

Revista Caatinga, 2016
Physalis peruviana L. is a perennial plant, but commonly referred as annual in commercial crops. The cultivation of this species might be successful in Brazilian subtropical areas with an adequate and planned management.
PEDRO HENRIQUE ABREU MOURA, GIVAGO COUTINHO, RAFAEL PIO, FLÁVIO GABRIEL BIANCHINI, PAULA NOGUEIRA CURI   +4 more
doaj  

Material choices for fibre in the Neolithic: an approach through the measurement of mechanical properties [PDF]

, 2016
Studies of the Mesolithic-Neolithic transition in Europe have focused on plants and animals exploited for food. However, the exploitation of plants for fibres underwent a significant change with the addition of domestic flax as a fibre crop.
Haigh, Sarah, Handley, Adrian, Harris, Susanna, Sampson, William   +3 more
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

An Effective Quality Control of Pharmacologically Active Volatiles of Houttuynia cordata Thunb by Fast Gas Chromatography-Surface Acoustic Wave Sensor

Molecules, 2015
Fast gas chromatography-surface acoustic wave sensor (GC/SAW) has been applied for the detection of the pharmacological volatiles emanated from Houttuynia cordata Thunb which is from South Korea. H.
Se Yeon Oh
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Degradation of lignin β-aryl ether units in Arabidopsis thaliana expressing LigD, LigF and LigG from Sphingomonas paucimobilis SYK-6 [PDF]

, 2017
Lignin is a major polymer in the secondary plant cell wall and composed of hydrophobic interlinked hydroxyphenylpropanoid units. The presence of lignin hampers conversion of plant biomass into biofuels; plants with modified lignin are therefore being ...
Bent, Board, Boerjan, Bonawitz, Bonawitz, Borkhardt, Buanafina, Davin, Dima, Dixon, Dixon, El Amrani, Felipe, Foyer, Gall, Gall, Geu-Flores, Geu-Flores, Goodin, Hause, Herbers, Huang, Kirk, Lallement, Lallement, Lazo, Li, Liu, Liu, Lu, Lu, Mansfield, Masai, Masai, Matsuda, Meux, Morreel, Morreel, Niculaes, Otter, Pauly, Rahimi, Ralph, Ralph, Rogers, Samalova, Sato, Sederoff, Shen, Sonoki, Strack, Tsuji, Van Acker, Vanholme, Vanholme, Vanholme, Vanholme, Vogel, Welinder, Weng, Øbro, Øbro   +61 more
core   +1 more source

Plant stem cells as innovation in cosmetics. [PDF]

Acta poloniae pharmaceutica, 2014
The stem cells thanks to their ability of unlimited division number or transformation into different cell types creating organs, are responsible for regeneration processes. Depending on the organism in which the stem cells exists, they divide to the plant or animal ones.
Moruś, Martyna, Baran, Monika, Rost-Roszkowska, Magdalena, Skotnicka-Graca, Urszula   +3 more
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Ultrasound Pulse Emission Spectroscopy Method to Characterize Xylem Conduits in Plant Stems. [PDF]

Research (Wash D C), 2022
Dutta S, Chen Z, Kaiser E, Matamoros PM, Steeneken PG, Verbiest GJ.   +5 more
europepmc   +1 more source